SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 7 VAL A 180
LEU A 144
LEU A 365
LEU A 364
 None
 0.83A 1cqpA-3g7uA:
undetectable
1cqpB-3g7uA:
2.3		 1cqpA-3g7uA:
18.59
1cqpB-3g7uA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 PHE A   7
GLU A  29
ASP A  51
PRO A  78
 None
 0.87A 1hmyA-3g7uA:
25.2		 1hmyA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 PHE A   7
GLU A  29
PRO A  78
LEU A  97
 None
 0.57A 1hmyA-3g7uA:
25.2		 1hmyA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 7 PHE A 334
PHE A 332
PHE A  42
HIS A  38
 None
 0.98A 1lh6A-3g7uA:
undetectable		 1lh6A-3g7uA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A 224
ASP A 330
TYR A 225
LEU A 325
PRO A 157
 None
 1.34A 1p33A-3g7uA:
8.9		 1p33A-3g7uA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 GLY A  11
GLY A  12
ILE A  30
ASP A  31
ASP A  51
PRO A  78
 None
 0.87A 1sqfA-3g7uA:
9.7		 1sqfA-3g7uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 TYR A 141
ILE A  73
VAL A 137
MET A  99
PHE A 101
 None
 1.10A 1uduB-3g7uA:
undetectable		 1uduB-3g7uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ARG A 315
LEU A 325
ALA A 323
LEU A 195
 None
 0.92A 1ukbA-3g7uA:
5.3		 1ukbA-3g7uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 10 TYR A 141
ILE A  73
VAL A 137
MET A  99
PHE A 101
 None
 1.16A 1xp0A-3g7uA:
undetectable		 1xp0A-3g7uA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 11 GLU A  29
ILE A  30
ASP A  31
ALA A  34
ASP A  51
PRO A  78
 None
 0.70A 2admA-3g7uA:
9.6		 2admA-3g7uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLU A  29
ILE A  30
ALA A  34
ASP A  51
PRO A  78
 None
 0.74A 2admB-3g7uA:
9.2		 2admB-3g7uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 PRO A 188
THR A 190
PRO A 157
 None
 0.85A 2d55C-3g7uA:
undetectable		 2d55C-3g7uA:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 PHE A   7
GLY A   9
GLY A  12
ASP A  31
ASP A  51
VAL A 349
 None
None
None
None
None
CL  A 401 ( 4.0A)
 0.99A 2hmyB-3g7uA:
25.1		 2hmyB-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
ASP A  31
PRO A  78
LEU A  97
VAL A 349
 None
None
None
None
None
None
CL  A 401 ( 4.0A)
 0.84A 2hmyB-3g7uA:
25.1		 2hmyB-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 5 PHE A 334
PHE A 332
PHE A  42
HIS A  38
 None
 1.01A 2lh6A-3g7uA:
undetectable		 2lh6A-3g7uA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A  13
ALA A 115
ILE A 121
ILE A 147
VAL A 349
 None
None
None
None
CL  A 401 ( 4.0A)
 1.08A 2nnpB-3g7uA:
undetectable		 2nnpB-3g7uA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 ASP A   5
GLY A   9
LEU A  13
ILE A  30
ASP A  31
LEU A  97
 None
 0.88A 2nxeA-3g7uA:
9.0		 2nxeA-3g7uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 12 ASP A   5
GLY A   9
LEU A  13
ILE A  30
ASP A  31
LEU A  97
 None
 0.82A 2nxeB-3g7uA:
9.0		 2nxeB-3g7uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A   9
ILE A  30
ASP A  51
VAL A  52
GLY A  76
 None
 0.72A 2qe6A-3g7uA:
6.4		 2qe6A-3g7uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A   9
ILE A  30
ASP A  51
VAL A  52
GLY A  76
 None
 0.87A 2qe6B-3g7uA:
6.6		 2qe6B-3g7uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A 327
GLY A  16
SER A 350
GLU A 355
ASP A  23
 None
 1.15A 2wa2A-3g7uA:
8.0		 2wa2A-3g7uA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A   7
GLY A   9
ILE A  30
ASP A  51
VAL A  52
 None
 0.71A 2zzmA-3g7uA:
8.5		 2zzmA-3g7uA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
LEU A  13
LEU A  97
ASN A 347
VAL A 349
 None
None
None
None
None
None
CL  A 401 ( 4.0A)
 0.50A 3av6A-3g7uA:
18.9		 3av6A-3g7uA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
LEU A  13
PRO A  78
LEU A  97
VAL A 349
 None
None
None
None
None
None
CL  A 401 ( 4.0A)
 0.95A 3av6A-3g7uA:
18.9		 3av6A-3g7uA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 10 PHE A   7
GLY A   9
ILE A  30
ASP A  51
VAL A  52
 None
 0.76A 3ay0B-3g7uA:
8.5		 3ay0B-3g7uA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 TYR A 141
ILE A  73
VAL A 137
MET A  99
PHE A 101
 None
 1.14A 3b2rB-3g7uA:
undetectable		 3b2rB-3g7uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP A   5
LEU A  13
ILE A  30
ASP A  31
LEU A  97
 None
 0.78A 3cjtC-3g7uA:
9.4		 3cjtC-3g7uA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A   9
LEU A  13
ILE A  30
ASP A  31
LEU A  97
 None
 0.87A 3cjtG-3g7uA:
9.4		 3cjtG-3g7uA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A   7
GLY A  12
ASP A  31
ASP A  51
ASN A 347
 None
 0.85A 3eeoA-3g7uA:
20.3		 3eeoA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A   7
GLY A  12
ASP A  31
ASP A  51
PRO A  78
 None
 1.08A 3eeoA-3g7uA:
20.3		 3eeoA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A   7
GLY A  12
ASP A  31
PRO A  78
LEU A  97
 None
 1.04A 3eeoA-3g7uA:
20.3		 3eeoA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 7 ILE A 121
LYS A 125
ILE A 129
TYR A 102
 None
None
None
GOL  A 402 ( 4.3A)
 1.06A 3eteD-3g7uA:
3.4
3eteF-3g7uA:
3.4		 3eteD-3g7uA:
20.94
3eteF-3g7uA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A   9
GLU A  29
ASP A  31
ASP A  51
PRO A  78
 None
 0.87A 3fuuA-3g7uA:
8.9		 3fuuA-3g7uA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLU A  29
ILE A  30
ASP A  31
ASP A  51
PRO A  78
 None
 0.74A 3grvA-3g7uA:
10.0		 3grvA-3g7uA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A  29
ILE A  30
ASP A  31
ASP A  51
PRO A  78
 None
 0.69A 3gryA-3g7uA:
10.3		 3gryA-3g7uA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 SER A  45
PHE A  42
ASP A   5
PRO A 233
 None
 1.11A 3jq7B-3g7uA:
9.6		 3jq7B-3g7uA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A  13
ALA A 115
ILE A 121
ILE A 147
VAL A 349
 None
None
None
None
CL  A 401 ( 4.0A)
 1.14A 3mwsB-3g7uA:
undetectable		 3mwsB-3g7uA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 9 PRO A 308
ALA A 322
ILE A 317
THR A  37
PHE A 334
 None
 1.44A 3qelD-3g7uA:
2.3		 3qelD-3g7uA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 11 GLY A   9
ASP A  31
ASP A  51
VAL A  52
PRO A  78
 None
 1.07A 3v8vB-3g7uA:
5.4		 3v8vB-3g7uA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 6 GLY A   9
GLU A  29
ASP A  51
ASP A   5
 None
 0.96A 3vywC-3g7uA:
6.7		 3vywC-3g7uA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 HIS A 100
GLU A  50
ARG A 103
ILE A  60
 None
 1.26A 4cx7A-3g7uA:
undetectable
4cx7B-3g7uA:
undetectable		 4cx7A-3g7uA:
21.14
4cx7B-3g7uA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 4 PHE A 224
VAL A 189
ALA A 156
PHE A 288
 None
 1.28A 4f3tA-3g7uA:
2.8		 4f3tA-3g7uA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 GLU A  29
ASP A  31
ASP A  51
 None
 0.48A 4gc9A-3g7uA:
7.2		 4gc9A-3g7uA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 4 PHE A 224
VAL A 189
ALA A 156
PHE A 288
 None
 1.33A 4w5rA-3g7uA:
2.9		 4w5rA-3g7uA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 4 PHE A 224
VAL A 189
ALA A 156
PHE A 288
 None
 1.30A 4w5tA-3g7uA:
3.1		 4w5tA-3g7uA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP A  51
PRO A  78
PHE A   7
GLY A   9
GLU A  29
 None
 0.77A 5hfjD-3g7uA:
2.2		 5hfjD-3g7uA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP A  51
PRO A  78
PHE A   7
GLY A   9
GLU A  29
 None
 0.86A 5hfjF-3g7uA:
2.5		 5hfjF-3g7uA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		6 / 11 ARG A  94
PHE A   7
ILE A  30
ASP A  51
VAL A  52
PRO A  78
 None
 1.10A 5hjiA-3g7uA:
9.4		 5hjiA-3g7uA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 11 PHE A   7
GLY A   9
GLU A  29
ILE A  30
ASP A  51
VAL A  52
PRO A  78
 None
 0.79A 5hjiA-3g7uA:
9.4		 5hjiA-3g7uA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 8 HIS A  47
HIS A  38
GLY A  11
SER A  14
 None
 0.98A 5m8rC-3g7uA:
undetectable		 5m8rC-3g7uA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 214
ARG A 315
ARG A 320
 None
 1.01A 5vcgA-3g7uA:
undetectable		 5vcgA-3g7uA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		4 / 7 VAL A 105
LEU A  15
PHE A 112
LEU A 358
 None
 0.97A 6aycA-3g7uA:
undetectable		 6aycA-3g7uA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 361
GLY A  72
PHE A 101
 None
 0.52A 6exiC-3g7uA:
3.1		 6exiC-3g7uA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
ASP A  31
ASP A  51
ASN A 347
SER A 348
 None
 0.84A 6mhtA-3g7uA:
24.8		 6mhtA-3g7uA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Escherichia
coli) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
ASP A  31
ASP A  51
ASN A 347
VAL A 349
 None
None
None
None
None
None
CL  A 401 ( 4.0A)
 0.90A 6mhtA-3g7uA:
24.8		 6mhtA-3g7uA:
29.05