SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 THR A  33
ALA A  36
ASP A  37
LEU A  40
LEU A  72
 None
 1.19A 1errA-3g87A:
undetectable		 1errA-3g87A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 4 THR A 109
LEU A 113
LEU A 120
GLN A 123
 None
 0.85A 1fbmA-3g87A:
undetectable		 1fbmA-3g87A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 5 THR A 109
LEU A 113
LEU A 120
GLN A 123
 None
 0.84A 1fbmE-3g87A:
undetectable		 1fbmE-3g87A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 7 LEU A 113
PHE A 207
LEU A 216
SER A 225
 None
 0.90A 1wrlE-3g87A:
undetectable
1wrlF-3g87A:
undetectable		 1wrlE-3g87A:
12.50
1wrlF-3g87A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 113
ILE A 245
SER A 228
SER A  92
PHE A  96
 None
 1.37A 1xotB-3g87A:
undetectable		 1xotB-3g87A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A 110
LEU A  88
VAL A 223
TYR A 232
SER A 225
 None
 1.25A 2vqyA-3g87A:
undetectable		 2vqyA-3g87A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 6 VAL A 184
VAL A 133
GLN A 290
ARG A 185
 None
 1.16A 3bjwF-3g87A:
undetectable		 3bjwF-3g87A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 8 LEU A  99
TYR A 232
VAL A 249
GLY A  94
 None
 0.71A 4eq4B-3g87A:
undetectable		 4eq4B-3g87A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 5 THR A  62
THR A  59
HIS A  91
ASN A  70
 None
 1.27A 4pgfB-3g87A:
undetectable		 4pgfB-3g87A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 THR A  33
ALA A  36
ASP A  37
LEU A 111
LEU A  72
 None
 1.01A 4xi3B-3g87A:
undetectable		 4xi3B-3g87A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 11 LEU A  40
ALA A  36
LEU A  47
GLY A  22
LEU A  72
 None
 1.23A 5dxgB-3g87A:
undetectable		 5dxgB-3g87A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 9 GLN A  60
LEU A  47
ALA A 118
VAL A 114
ALA A  65
 None
 1.23A 5g44A-3g87A:
undetectable		 5g44A-3g87A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  98
GLN A  17
PHE A  11
GLY A  13
THR A  62
 None
 1.22A 5hfjB-3g87A:
undetectable		 5hfjB-3g87A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  98
GLN A  17
PHE A  11
GLY A  13
THR A  62
 None
 1.32A 5hfjC-3g87A:
undetectable		 5hfjC-3g87A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  98
GLN A  17
PHE A  11
GLY A  13
THR A  62
 None
 1.36A 5hfjG-3g87A:
undetectable		 5hfjG-3g87A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 7 ILE A  44
LEU A  47
LEU A  56
PRO A  64
 None
 0.95A 5u4sA-3g87A:
undetectable		 5u4sA-3g87A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A  44
LEU A  47
LEU A  56
PRO A  64
 None
 0.91A 5u4sB-3g87A:
undetectable		 5u4sB-3g87A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		5 / 12 PHE A 199
ILE A 140
ALA A 131
ALA A 128
GLU A 171
 None
 1.27A 5vcgA-3g87A:
undetectable		 5vcgA-3g87A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 5 LEU A  32
LEU A 100
THR A  73
PRO A  85
 None
 1.05A 6ew0F-3g87A:
undetectable		 6ew0F-3g87A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A  32
LEU A 100
THR A  73
PRO A  85
 None
 1.06A 6ew0G-3g87A:
undetectable		 6ew0G-3g87A:
11.11