SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g8a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 12 LEU A 216
GLY A  21
GLY A  22
VAL A 101
LEU A  18
LEU A  29
None
1.41A 1mx1D-3g8aA:
3.1
1mx1D-3g8aA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 10 ALA A 118
PHE A 119
ALA A 123
LEU A 127
LEU A  39
None
1.10A 2bxqA-3g8aA:
2.3
2bxqA-3g8aA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
8 / 12 GLY A  88
GLY A  90
ASP A 111
ALA A 112
THR A 113
ALA A 139
GLU A 140
ARG A 158
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
0.66A 2gluA-3g8aA:
16.6
2gluA-3g8aA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 12 GLY A  88
GLY A  90
ALA A 112
THR A 113
ALA A 139
ARG A 158
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.9A)
0.84A 2gluB-3g8aA:
14.2
2gluB-3g8aA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 6 PRO A 197
LEU A 206
ARG A 201
GLY A 203
None
1.23A 2hs2B-3g8aA:
undetectable
2hs2B-3g8aA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
3 / 3 PRO A 172
LEU A 202
ARG A 201
None
0.91A 3aqiA-3g8aA:
2.7
3aqiA-3g8aA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 6 TYR A 152
ALA A 155
LEU A  85
ALA A 139
None
None
None
SAH  A 303 (-3.8A)
0.93A 3b6hB-3g8aA:
undetectable
3b6hB-3g8aA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 12 LEU A  87
GLY A  88
GLY A  90
LEU A 109
LEU A 166
None
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
None
1.19A 3cjtG-3g8aA:
15.3
3cjtG-3g8aA:
28.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 10 ALA A 139
GLU A 140
LEU A 170
LEU A 169
LEU A  85
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
None
SAH  A 303 ( 4.9A)
None
1.49A 3erdB-3g8aA:
undetectable
3erdB-3g8aA:
24.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
11 / 11 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.31A 3g88A-3g8aA:
36.8
3g88A-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 11 GLY A  90
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 157
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
None
1.35A 3g88A-3g8aA:
36.8
3g88A-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
11 / 11 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.31A 3g88B-3g8aA:
36.7
3g88B-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 11 GLY A  90
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 157
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
None
1.35A 3g88B-3g8aA:
36.7
3g88B-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
12 / 12 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
LYS A 116
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.38A 3g89A-3g8aA:
36.6
3g89A-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 12 GLY A  90
PHE A  93
THR A 113
LYS A 116
GLU A 244
SAH  A 303 (-3.5A)
None
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
None
0.94A 3g89A-3g8aA:
36.6
3g89A-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
11 / 11 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.25A 3g89B-3g8aA:
36.6
3g89B-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 11 GLY A  90
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 157
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
None
1.32A 3g89B-3g8aA:
36.6
3g89B-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
12 / 12 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
LYS A 116
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.41A 3g8bA-3g8aA:
36.0
3g8bA-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 12 GLY A  90
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 157
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
None
1.33A 3g8bA-3g8aA:
36.0
3g8bA-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 12 GLY A  90
PHE A  93
THR A 113
LYS A 116
GLU A 244
SAH  A 303 (-3.5A)
None
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
None
0.96A 3g8bA-3g8aA:
36.0
3g8bA-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
12 / 12 GLY A  88
GLY A  90
PHE A  93
ASP A 111
ALA A 112
THR A 113
LYS A 116
ARG A 138
ALA A 139
GLU A 140
ARG A 158
ALA A 159
SAH  A 303 (-3.0A)
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
SAH  A 303 (-3.7A)
SAH  A 303 (-3.8A)
SAH  A 303 (-3.4A)
SAH  A 303 (-3.9A)
SAH  A 303 (-3.9A)
0.44A 3g8bB-3g8aA:
40.3
3g8bB-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 12 GLY A  90
ASP A 111
ALA A 112
THR A 113
ARG A 138
ALA A 157
SAH  A 303 (-3.5A)
SAH  A 303 (-2.9A)
SAH  A 303 (-3.6A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.7A)
None
1.32A 3g8bB-3g8aA:
40.3
3g8bB-3g8aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 12 GLY A  90
PHE A  93
ASP A 111
THR A 113
LYS A 116
GLU A 244
SAH  A 303 (-3.5A)
None
SAH  A 303 (-2.9A)
SAH  A 303 (-4.2A)
SAH  A 303 (-3.6A)
None
1.22A 3g8bB-3g8aA:
40.3
3g8bB-3g8aA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 7 GLU A 150
TYR A 152
ARG A  83
GLY A 147
None
1.07A 4fgzA-3g8aA:
12.1
4fgzA-3g8aA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 8 GLU A 150
TYR A 152
ARG A  83
GLY A 147
None
0.98A 4fgzA-3g8aA:
12.1
4fgzB-3g8aA:
12.2
4fgzA-3g8aA:
19.10
4fgzB-3g8aA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 12 LEU A 166
LEU A 171
ALA A 180
VAL A 224
ALA A 182
None
1.23A 4x1iB-3g8aA:
undetectable
4x1iB-3g8aA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 8 ALA A 180
LEU A 171
LEU A 199
LEU A 195
ALA A 182
None
1.09A 4z90A-3g8aA:
undetectable
4z90B-3g8aA:
undetectable
4z90C-3g8aA:
undetectable
4z90D-3g8aA:
undetectable
4z90E-3g8aA:
undetectable
4z90A-3g8aA:
18.55
4z90B-3g8aA:
18.55
4z90C-3g8aA:
18.55
4z90D-3g8aA:
18.55
4z90E-3g8aA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 7 LEU A 195
LEU A 163
ALA A 182
ALA A 180
LEU A 199
None
1.17A 4z90F-3g8aA:
undetectable
4z90G-3g8aA:
undetectable
4z90H-3g8aA:
undetectable
4z90J-3g8aA:
undetectable
4z90F-3g8aA:
18.55
4z90G-3g8aA:
18.55
4z90H-3g8aA:
18.55
4z90J-3g8aA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
6 / 11 MET A 183
LEU A 223
LEU A  82
LEU A  98
LEU A  72
LEU A 105
None
1.38A 4zowA-3g8aA:
undetectable
4zowA-3g8aA:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 7 VAL A 224
ALA A 182
LEU A 206
LEU A 199
None
0.42A 5jq7A-3g8aA:
undetectable
5jq7A-3g8aA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 10 VAL A 224
ALA A 182
LEU A 206
LEU A 199
LEU A 192
None
0.69A 6f5uA-3g8aA:
undetectable
6f5uB-3g8aA:
undetectable
6f5uA-3g8aA:
15.61
6f5uB-3g8aA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
5 / 10 VAL A 224
ALA A 182
LEU A 206
LEU A 199
LEU A 192
None
0.64A 6f6nA-3g8aA:
undetectable
6f6nB-3g8aA:
undetectable
6f6nA-3g8aA:
15.61
6f6nB-3g8aA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus)
4 / 7 ARG A 133
TYR A 152
HIS A 148
LEU A  87
None
1.29A 6g2pA-3g8aA:
2.1
6g2pA-3g8aA:
22.52