SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 6 ILE A 200
PHE A 147
PHE A 156
TYR A 198
 None
 1.28A 3elzB-3g8kA:
undetectable		 3elzB-3g8kA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 7 ILE A 180
PHE A 147
PHE A 156
GLY A 201
 None
 1.03A 3em0B-3g8kA:
undetectable		 3em0B-3g8kA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 7 TYR A 198
LEU A 178
LEU A 189
SER A 239
 None
 0.94A 3lm8A-3g8kA:
undetectable
3lm8C-3g8kA:
undetectable		 3lm8A-3g8kA:
19.72
3lm8C-3g8kA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 7 TYR A 198
LEU A 178
LEU A 189
SER A 239
 None
 1.02A 3lm8B-3g8kA:
undetectable
3lm8D-3g8kA:
undetectable		 3lm8B-3g8kA:
19.72
3lm8D-3g8kA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 8 TYR A 198
LEU A 178
LEU A 189
SER A 239
 None
 0.94A 3lm8B-3g8kA:
undetectable
3lm8D-3g8kA:
undetectable		 3lm8B-3g8kA:
19.72
3lm8D-3g8kA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 8 THR A 241
TYR A 198
ARG A 242
LEU A 243
 None
 1.20A 3wipG-3g8kA:
undetectable
3wipH-3g8kA:
undetectable		 3wipG-3g8kA:
16.89
3wipH-3g8kA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1
(Mus
musculus) 		4 / 8 ARG A 242
LEU A 243
THR A 241
TYR A 198
 None
 1.21A 3wipF-3g8kA:
undetectable
3wipJ-3g8kA:
undetectable		 3wipF-3g8kA:
16.89
3wipJ-3g8kA:
16.89