SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		4 / 4 ALA A 219
VAL A 215
ALA A 214
HIS A 168
 None
 1.00A 1q23A-3g8rA:
undetectable		 1q23A-3g8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		3 / 3 VAL A 215
ALA A 214
HIS A 168
 None
 0.73A 1q23G-3g8rA:
undetectable		 1q23G-3g8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		4 / 4 ALA A 219
VAL A 215
ALA A 214
HIS A 168
 None
 1.09A 1q23K-3g8rA:
undetectable		 1q23K-3g8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		5 / 10 LEU A 338
VAL A 299
VAL A 288
LEU A 310
TYR A 321
 None
 1.46A 1sv5A-3g8rA:
undetectable		 1sv5A-3g8rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		4 / 5 LEU A 164
ILE A 117
ILE A 131
ALA A 132
 None
 0.78A 2i2zA-3g8rA:
undetectable		 2i2zA-3g8rA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		4 / 4 LEU A 164
ILE A 117
ILE A 131
ALA A 132
 None
 0.85A 2i30A-3g8rA:
undetectable		 2i30A-3g8rA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		4 / 6 MET A  12
LEU A  45
MET A  87
GLU A  86
 None
 1.22A 2kuhA-3g8rA:
undetectable		 2kuhA-3g8rA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		3 / 3 HIS A  16
MET A  80
MET A  12
 None
 1.14A 2vj1A-3g8rA:
undetectable		 2vj1A-3g8rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		5 / 12 LEU A 338
VAL A 299
VAL A 288
LEU A 310
TYR A 321
 None
 1.46A 3megA-3g8rA:
undetectable		 3megA-3g8rA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		5 / 10 ILE A 197
VAL A 221
ILE A 117
ILE A 166
THR A 220
 None
 1.38A 3um5A-3g8rA:
undetectable		 3um5A-3g8rA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		5 / 12 LEU A 338
VAL A 299
VAL A 288
LEU A 310
TYR A 321
 None
 1.34A 5cymA-3g8rA:
undetectable		 5cymA-3g8rA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		3 / 3 LYS A   5
ASP A  40
ARG A 196
 None
 0.99A 5jwaA-3g8rA:
undetectable
5jwaH-3g8rA:
undetectable		 5jwaA-3g8rA:
20.48
5jwaH-3g8rA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 3g8r PROBABLE SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
E
(Chromobacterium
violaceum) 		3 / 3 PHE A   8
ASP A  40
LYS A   5
 None
 0.84A 6awtD-3g8rA:
undetectable		 6awtD-3g8rA:
17.14