SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 267
GLY A 266
LEU A 326
TYR A 349
VAL A 345
 None
 1.03A 1fduA-3g8yA:
2.8		 1fduA-3g8yA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 267
GLY A 266
LEU A 326
TYR A 349
VAL A 345
 None
 1.11A 1fduC-3g8yA:
3.5		 1fduC-3g8yA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 141
GLY A 254
LEU A 257
GLY A 145
ARG A 148
 None
None
None
EDO  A   4 (-3.5A)
PEG  A  13 ( 3.5A)
 1.17A 1y4lA-3g8yA:
undetectable		 1y4lA-3g8yA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CB8_A_SAMA501_0
(PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 387
SER A 256
GLU A 260
ASP A 279
VAL A 391
 None
EDO  A   4 ( 3.8A)
EDO  A   9 ( 4.6A)
EDO  A   2 (-3.6A)
None
 1.41A 3cb8A-3g8yA:
1.7		 3cb8A-3g8yA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ILE A 143
PRO A 261
SER A 146
GLY A 258
 None
 0.88A 3lslA-3g8yA:
undetectable
3lslD-3g8yA:
undetectable		 3lslA-3g8yA:
20.55
3lslD-3g8yA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ALA A 193
LEU A 217
ALA A 191
ASN A 190
LEU A 309
 None
 1.15A 3r9cA-3g8yA:
undetectable		 3r9cA-3g8yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 LEU A 265
LEU A 141
PRO A 144
ILE A 143
 None
 0.89A 3s56B-3g8yA:
undetectable		 3s56B-3g8yA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 ILE A 143
PRO A 261
SER A 146
GLY A 258
 None
 0.74A 3tkdB-3g8yA:
undetectable		 3tkdB-3g8yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 ILE A 143
PRO A 261
SER A 146
GLY A 258
 None
 0.74A 3tkdA-3g8yA:
undetectable		 3tkdA-3g8yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 THR A 228
GLY A 226
ILE A 310
LEU A 217
 None
None
EDO  A   9 (-4.6A)
None
 1.19A 4ac9C-3g8yA:
2.7		 4ac9C-3g8yA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 THR A 228
GLY A 226
ILE A 310
LEU A 217
 None
None
EDO  A   9 (-4.6A)
None
 1.21A 4acaC-3g8yA:
2.5		 4acaC-3g8yA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 LEU A 257
ARG A 307
ILE A 310
ASN A 318
 None
None
EDO  A   9 (-4.6A)
None
 1.29A 4i00A-3g8yA:
undetectable		 4i00A-3g8yA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 VAL A  83
MET A  82
ALA A  81
PHE A 317
 None
None
EDO  A   6 ( 4.2A)
None
 1.08A 4lb2A-3g8yA:
undetectable		 4lb2A-3g8yA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 287
ARG A 340
ASP A 341
TYR A 387
 None
 1.46A 5a06A-3g8yA:
2.3		 5a06A-3g8yA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 287
ARG A 340
ASP A 341
TYR A 387
 None
 1.45A 5a06C-3g8yA:
3.5		 5a06C-3g8yA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 287
ARG A 340
ASP A 341
TYR A 387
 None
 1.45A 5a06D-3g8yA:
2.1		 5a06D-3g8yA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 287
ARG A 340
ASP A 341
TYR A 387
 None
 1.46A 5a06E-3g8yA:
2.0		 5a06E-3g8yA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 287
ARG A 340
ASP A 341
TYR A 387
 None
 1.46A 5a06F-3g8yA:
2.1		 5a06F-3g8yA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 GLY A 258
GLY A 145
SER A 146
LEU A 257
ARG A 307
 None
EDO  A   4 (-3.5A)
None
None
None
 1.12A 5hwkA-3g8yA:
undetectable		 5hwkA-3g8yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 GLY A 258
GLY A 145
SER A 146
LEU A 257
ARG A 307
 None
EDO  A   4 (-3.5A)
None
None
None
 1.12A 5hwkB-3g8yA:
undetectable		 5hwkB-3g8yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 PHE A 388
VAL A 393
TYR A 363
ASP A 279
 EDO  A   2 (-4.6A)
None
None
EDO  A   2 (-3.6A)
 0.99A 5iwuA-3g8yA:
undetectable		 5iwuA-3g8yA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 LEU A 378
GLY A 381
THR A 386
GLU A 389
ALA A 390
 None
 0.93A 5o96G-3g8yA:
undetectable		 5o96G-3g8yA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 186
PRO A  89
PHE A  88
PHE A 118
PRO A  97
 None
EDO  A   7 ( 4.5A)
None
None
None
 1.31A 6becA-3g8yA:
undetectable
6becB-3g8yA:
undetectable
6becC-3g8yA:
undetectable		 6becA-3g8yA:
22.39
6becB-3g8yA:
22.39
6becC-3g8yA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 186
PRO A  89
PHE A  88
PRO A  97
PHE A 115
 None
EDO  A   7 ( 4.5A)
None
None
None
 1.38A 6becA-3g8yA:
undetectable
6becB-3g8yA:
undetectable
6becC-3g8yA:
undetectable		 6becA-3g8yA:
22.39
6becB-3g8yA:
22.39
6becC-3g8yA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3g8y SUSD/RAGB-ASSOCIATED
ESTERASE-LIKE
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ASP A 341
ASP A 279
ASN A 190
 None
EDO  A   2 (-3.6A)
None
 0.86A 6gngB-3g8yA:
5.5		 6gngB-3g8yA:
20.88