SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g8z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3g8z PROTEIN OF UNKNOWN
FUNCTION WITH
CYSTATIN-LIKE FOLD
(Xanthomonas
campestris) 		4 / 4 SER A  68
PHE A  86
GLU A  85
GLY A  99
 None
 1.29A 1icvA-3g8zA:
undetectable
1icvB-3g8zA:
undetectable		 1icvA-3g8zA:
20.18
1icvB-3g8zA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3g8z PROTEIN OF UNKNOWN
FUNCTION WITH
CYSTATIN-LIKE FOLD
(Xanthomonas
campestris) 		5 / 12 TYR A  73
LEU A 103
ILE A  26
ILE A  82
ALA A  70
 None
None
None
None
CL  A 131 (-4.3A)
 1.09A 3vw1B-3g8zA:
undetectable		 3vw1B-3g8zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 3g8z PROTEIN OF UNKNOWN
FUNCTION WITH
CYSTATIN-LIKE FOLD
(Xanthomonas
campestris) 		5 / 12 ILE A  11
ALA A   7
ILE A 110
LEU A  54
ILE A  14
 None
None
None
None
GOL  A 133 (-4.8A)
 1.08A 4km0B-3g8zA:
undetectable		 4km0B-3g8zA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3g8z PROTEIN OF UNKNOWN
FUNCTION WITH
CYSTATIN-LIKE FOLD
(Xanthomonas
campestris) 		4 / 7 HIS A  44
ASN A  37
HIS A  38
ARG A 129
 None
 0.96A 4p6sB-3g8zA:
undetectable		 4p6sB-3g8zA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3g8z PROTEIN OF UNKNOWN
FUNCTION WITH
CYSTATIN-LIKE FOLD
(Xanthomonas
campestris) 		5 / 12 GLY A 128
SER A  41
SER A  61
ASP A 124
ALA A 125
 None
 1.35A 4ymgB-3g8zA:
undetectable		 4ymgB-3g8zA:
21.90