SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC32_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3g98	ALANYL-TRNA SYNTHETASE (Aquifex aeolicus)	5 / 6	GLY A 837 GLY A 836 GLY A 835 GLY A 846 GLY A 848	None	1.47A	3bogA-3g98A: undetectable 3bogC-3g98A: undetectable	3bogA-3g98A: undetectable 3bogC-3g98A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	3g98	ALANYL-TRNA SYNTHETASE (Aquifex aeolicus)	5 / 12	PHE A 797 ALA A 857 ILE A 806 ARG A 801 GLY A 837	None	1.30A	3lbdA-3g98A: undetectable	3lbdA-3g98A: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_B_FFOB403_0 (THYMIDYLATE SYNTHASE)	3g98	ALANYL-TRNA SYNTHETASE (Aquifex aeolicus)	5 / 10	PHE A 808 ILE A 826 ASN A 821 LEU A 843 GLY A 811	None	1.50A	6r2eB-3g98A: undetectable	6r2eB-3g98A: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_D_FFOD403_0 (THYMIDYLATE SYNTHASE)	3g98	ALANYL-TRNA SYNTHETASE (Aquifex aeolicus)	5 / 10	PHE A 808 ILE A 826 ASN A 821 LEU A 843 GLY A 811	None	1.44A	6r2eD-3g98A: undetectable	6r2eD-3g98A: 16.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BOG_C_DHIC32_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","3g98","ALANYL-TRNA SYNTHETASE","Aquifex aeolicus",5,"GLY A 837;GLY A 836;GLY A 835;GLY A 846;GLY A 848","None","1.47A","3bogA-3g98A:undetectable;3bogC-3g98A:undetectable","3bogA-3g98A:undetectable;3bogC-3g98A:undetectable"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","3g98","ALANYL-TRNA SYNTHETASE","Aquifex aeolicus",5,"PHE A 797;ALA A 857;ILE A 806;ARG A 801;GLY A 837","None","1.30A","3lbdA-3g98A:undetectable","3lbdA-3g98A:17.83"],["6R2E_B_FFOB403_0","THYMIDYLATE SYNTHASE","3g98","ALANYL-TRNA SYNTHETASE","Aquifex aeolicus",5,"PHE A 808;ILE A 826;ASN A 821;LEU A 843;GLY A 811","None","1.50A","6r2eB-3g98A:undetectable","6r2eB-3g98A:16.77"],["6R2E_D_FFOD403_0","THYMIDYLATE SYNTHASE","3g98","ALANYL-TRNA SYNTHETASE","Aquifex aeolicus",5,"PHE A 808;ILE A 826;ASN A 821;LEU A 843;GLY A 811","None","1.44A","6r2eD-3g98A:undetectable","6r2eD-3g98A:16.77"]]