SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3g9a MINIMIZER
(Camelus
dromedarius) 		4 / 8 MET B  34
TYR B 102
ASP B 101
SER B  96
 None
 1.27A 2bteA-3g9aB:
undetectable		 2bteA-3g9aB:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3g9a MINIMIZER
(Camelus
dromedarius) 		4 / 8 MET B  34
TYR B 102
ASP B 101
SER B  96
 None
 1.33A 2bteD-3g9aB:
undetectable		 2bteD-3g9aB:
9.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 VAL B   2
ALA B  24
MET B  34
ARG B  71
ASN B  76
ALA B  94
 None
 0.90A 3qxtA-3g9aB:
20.0		 3qxtA-3g9aB:
66.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 VAL B   2
ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
 None
 0.77A 3qxtA-3g9aB:
20.0		 3qxtA-3g9aB:
66.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		8 / 12 VAL B   2
LEU B   4
ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
TYR B 102
 None
 0.71A 3qxtB-3g9aB:
20.2		 3qxtB-3g9aB:
66.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
TYR B 102
 None
 0.64A 3qxvA-3g9aB:
19.5		 3qxvA-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 VAL B   2
ALA B  24
MET B  34
VAL B  78
ALA B  94
TYR B 102
 None
 0.87A 3qxvA-3g9aB:
19.5		 3qxvA-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
TYR B 102
 None
 0.69A 3qxvB-3g9aB:
19.7		 3qxvB-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		5 / 11 ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
 None
 0.71A 3qxvC-3g9aB:
20.0		 3qxvC-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		7 / 12 VAL B   2
ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
TYR B 102
 None
 0.83A 3qxvD-3g9aB:
19.5		 3qxvD-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3g9a MINIMIZER
(Camelus
dromedarius) 		6 / 12 ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
TYR B 102
 None
 0.68A 3qxvE-3g9aB:
16.4		 3qxvE-3g9aB:
64.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3g9a MINIMIZER
(Camelus
dromedarius) 		5 / 12 VAL B  78
ALA B  35
THR B  98
GLY B  55
LEU B  52
 None
 1.14A 5m54E-3g9aB:
undetectable		 5m54E-3g9aB:
15.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 3g9a MINIMIZER
(Camelus
dromedarius) 		3 / 3 TYR B  59
GLY B  65
THR B  68
 None
 0.18A 6cjkB-3g9aB:
18.0		 6cjkB-3g9aB:
34.21