SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 10 ALA L  58
GLY L  62
ARG S 520
GLU L  87
LEU L  83
 None
None
GLU  S   2 (-4.2A)
None
None
 1.29A 1cmcA-3g9kL:
undetectable
1cmcB-3g9kL:
undetectable		 1cmcA-3g9kL:
15.48
1cmcB-3g9kL:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.21A 1fk9A-3g9kL:
undetectable		 1fk9A-3g9kL:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 11 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.15A 1fkpA-3g9kL:
undetectable		 1fkpA-3g9kL:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 GLY S 499
GLN S 501
VAL S 500
ILE S 455
GLY S 518
 None
 1.09A 1fohC-3g9kS:
undetectable		 1fohC-3g9kS:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 GLY S 499
GLN S 501
VAL S 500
ILE S 455
GLY S 518
 None
 1.09A 1fohD-3g9kS:
undetectable		 1fohD-3g9kS:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 11 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.17A 1jkhA-3g9kL:
undetectable
1jkhB-3g9kL:
undetectable		 1jkhA-3g9kL:
21.18
1jkhB-3g9kL:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.19A 1lw0A-3g9kL:
undetectable		 1lw0A-3g9kL:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.50A 1lw0A-3g9kL:
undetectable		 1lw0A-3g9kL:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.19A 1lwfA-3g9kL:
undetectable		 1lwfA-3g9kL:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 11 LEU S 371
GLU L 114
GLY L  96
ILE L  93
LEU L 185
 None
 1.22A 1p91A-3g9kS:
undetectable		 1p91A-3g9kS:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 GLY S 499
GLN S 501
VAL S 500
ILE S 455
GLY S 518
 None
 1.10A 1pn0C-3g9kS:
undetectable		 1pn0C-3g9kS:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 GLY S 499
GLN S 501
VAL S 500
ILE S 455
GLY S 518
 None
 1.10A 1pn0D-3g9kS:
undetectable		 1pn0D-3g9kS:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.33A 1sv5A-3g9kL:
undetectable		 1sv5A-3g9kL:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.12A 1vrtA-3g9kL:
undetectable		 1vrtA-3g9kL:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.44A 1vrtA-3g9kL:
undetectable		 1vrtA-3g9kL:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 LEU L 210
GLY L  84
GLY L  92
GLY L 131
LYS L 212
 None
 1.19A 1y4lA-3g9kL:
undetectable		 1y4lA-3g9kL:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 LEU L 274
GLY L 270
VAL S 415
HIS S 354
ILE S 433
 None
 1.42A 1z95A-3g9kL:
undetectable		 1z95A-3g9kL:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 12 LEU S 441
GLY L 258
ASP L 260
LEU L 277
LEU L 273
 None
 0.94A 2nxeA-3g9kS:
undetectable		 2nxeA-3g9kS:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 12 TYR L 138
ILE L 213
GLY L 135
VAL L 246
SER S 367
 None
 0.68A 2okcA-3g9kL:
undetectable		 2okcA-3g9kL:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		5 / 12 TYR L 138
ILE L 213
GLY L 135
VAL L 246
SER S 367
 None
 0.69A 2okcB-3g9kL:
undetectable		 2okcB-3g9kL:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 6 LEU S 451
TYR S 444
ILE S 425
ILE S 504
 None
 0.94A 2q8hA-3g9kS:
undetectable		 2q8hA-3g9kS:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 ALA L 227
TYR L 222
ALA L 218
GLY L 220
ILE L 213
 None
 1.24A 2v7bB-3g9kL:
undetectable		 2v7bB-3g9kL:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 8 THR S 363
MET L  99
ILE L 101
ASP S 359
 None
 1.07A 2xytH-3g9kS:
undetectable		 2xytH-3g9kS:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 THR S 363
MET L  99
ILE L 101
ASP S 359
 None
 1.03A 2xytI-3g9kS:
undetectable		 2xytI-3g9kS:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 MET L 136
VAL S 365
SER S 367
GLY L 135
ILE L 139
 None
 1.46A 3a65A-3g9kL:
undetectable		 3a65A-3g9kL:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 TYR L 189
LEU L 206
LEU L 185
PHE S 375
 None
 1.14A 3nk2X-3g9kL:
undetectable		 3nk2X-3g9kL:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 5 GLY L  98
ASP L 111
ARG L 113
MET L 276
 None
 1.28A 3qx3A-3g9kL:
undetectable		 3qx3A-3g9kL:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		4 / 7 ILE L 195
PHE S 375
PHE S 385
LEU L  88
 None
 0.85A 3v7pA-3g9kL:
undetectable		 3v7pA-3g9kL:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		3 / 3 LYS L 326
LYS L 322
PRO L 324
 None
 1.11A 4dv1L-3g9kL:
undetectable		 4dv1L-3g9kL:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 ASN S 369
GLY L  96
GLY L  97
PHE L 268
GLY L  95
 None
 1.47A 4h2gA-3g9kS:
undetectable		 4h2gA-3g9kS:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.30A 4hvcA-3g9kL:
undetectable		 4hvcA-3g9kL:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.26A 4hvcB-3g9kL:
undetectable		 4hvcB-3g9kL:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 11 GLY S 424
ALA S 515
GLY S 426
ILE S 471
LEU S 473
 None
 1.09A 4kt0A-3g9kS:
undetectable
4kt0J-3g9kS:
undetectable		 4kt0A-3g9kS:
11.98
4kt0J-3g9kS:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUF_A_ACTA605_0
(SERUM ALBUMIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		4 / 4 ALA S 495
HIS L  89
PHE S 374
LEU L 175
 None
None
GLU  S   2 (-4.2A)
None
 1.35A 4lufA-3g9kS:
undetectable		 4lufA-3g9kS:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.32A 4olfA-3g9kL:
undetectable		 4olfA-3g9kL:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.45A 4puoA-3g9kL:
0.0		 4puoA-3g9kL:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 8 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.38A 4puoC-3g9kL:
undetectable		 4puoC-3g9kL:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 9 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.37A 4q0bC-3g9kL:
undetectable		 4q0bC-3g9kL:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 8 LEU S 416
THR L 263
LEU S 437
LEU S 441
 None
 0.74A 4z90F-3g9kS:
undetectable
4z90G-3g9kS:
undetectable
4z90H-3g9kS:
undetectable
4z90I-3g9kS:
undetectable
4z90J-3g9kS:
undetectable		 4z90F-3g9kS:
19.63
4z90G-3g9kS:
19.63
4z90H-3g9kS:
19.63
4z90I-3g9kS:
19.63
4z90J-3g9kS:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 ILE S 436
ARG S 519
VAL S 500
ILE S 455
 None
 1.00A 4zzbC-3g9kS:
undetectable
4zzbD-3g9kS:
undetectable		 4zzbC-3g9kS:
18.12
4zzbD-3g9kS:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 8 SER S 367
GLY L  98
ILE L  93
GLY L 135
 None
 0.82A 5alcL-3g9kS:
undetectable		 5alcL-3g9kS:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		3 / 3 THR L 233
HIS L  89
LEU S 371
 None
 0.77A 5axdA-3g9kL:
undetectable		 5axdA-3g9kL:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		3 / 3 THR L 233
HIS L  89
LEU S 371
 None
 0.75A 5axdC-3g9kL:
undetectable		 5axdC-3g9kL:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		4 / 5 ARG S 360
LEU L  66
ASN L  68
VAL L  65
 None
 1.34A 5cshB-3g9kS:
undetectable		 5cshB-3g9kS:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 TYR L 138
HIS L 140
LEU L 152
GLY L 217
ILE L 213
 None
 1.02A 5d4uC-3g9kL:
undetectable		 5d4uC-3g9kL:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 TYR L 138
HIS L 140
LEU L 152
GLY L 217
ILE L 213
 None
 1.01A 5d4uD-3g9kL:
undetectable		 5d4uD-3g9kL:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 GLY S 424
GLY S 426
SER S 427
LEU L 273
 None
 0.79A 5izfA-3g9kS:
undetectable		 5izfA-3g9kS:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 GLY L 144
ALA L  76
ASP S 359
ASN L 142
 None
 0.96A 5mvsA-3g9kL:
undetectable		 5mvsA-3g9kL:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 8 GLY L 144
ALA L  76
ASP S 359
ASN L 142
 None
 0.96A 5mvsB-3g9kL:
undetectable		 5mvsB-3g9kL:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		4 / 7 GLU S 421
TYR L 259
ALA S 502
GLY S 514
 None
 0.68A 5uxdA-3g9kS:
undetectable		 5uxdA-3g9kS:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.17A 5xipC-3g9kL:
undetectable		 5xipC-3g9kL:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.24A 5xiqA-3g9kL:
undetectable		 5xiqA-3g9kL:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 12 GLU L  60
PRO L  56
GLU L  87
HIS L  89
GLY L  84
 None
 1.25A 5xiqD-3g9kL:
undetectable		 5xiqD-3g9kL:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.33A 6bsiA-3g9kL:
undetectable		 6bsiA-3g9kL:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis) 		5 / 10 LEU L 273
VAL L 261
VAL L 328
TYR L 256
GLY L 254
 None
 1.32A 6bsjA-3g9kL:
undetectable		 6bsjA-3g9kL:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD
CAPSULE BIOSYNTHESIS
PROTEIN CAPD
(Bacillus
anthracis;
Bacillus
anthracis) 		3 / 3 THR S 438
ALA L 280
LYS L 283
 None
 0.77A 6fgcA-3g9kS:
undetectable		 6fgcA-3g9kS:
17.76