SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 5 TYR A 254
LEU A 313
LYS A 315
HIS A 285
 None
 1.21A 2wekB-3g9qA:
0.6		 2wekB-3g9qA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A 114
GLU A 100
ILE A 102
 None
 0.60A 3czhA-3g9qA:
undetectable		 3czhA-3g9qA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A 132
ASP A 117
GLY A  81
VAL A 121
ILE A 119
 None
 0.91A 3em3B-3g9qA:
undetectable		 3em3B-3g9qA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 7 GLY A 199
ASP A 201
ILE A 202
VAL A 269
 None
 0.90A 3fi0E-3g9qA:
undetectable		 3fi0E-3g9qA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 11 LEU A 118
ALA A  65
VAL A 141
LEU A 146
GLN A 151
THR A 159
 None
 1.50A 3jwqB-3g9qA:
undetectable
3jwqC-3g9qA:
undetectable		 3jwqB-3g9qA:
18.96
3jwqC-3g9qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A 132
ASP A 117
GLY A  81
VAL A 121
ILE A 119
 None
 0.98A 3oxwD-3g9qA:
undetectable		 3oxwD-3g9qA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A  79
ALA A 136
LEU A 152
PHE A 155
THR A 159
 None
 1.42A 4iarA-3g9qA:
1.6		 4iarA-3g9qA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 4 TYR A 217
THR A 225
VAL A 204
ILE A 192
 None
 1.45A 4jx1F-3g9qA:
undetectable		 4jx1F-3g9qA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 222
LEU A 302
GLN A 305
ILE A 309
ILE A 183
 None
 0.95A 4ltwA-3g9qA:
undetectable		 4ltwA-3g9qA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 SER A 193
MET A 195
ASP A 234
 None
 0.89A 4mm4B-3g9qA:
undetectable		 4mm4B-3g9qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3g9q FERRICHROME-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A 222
ILE A 216
TYR A 287
 None
 0.69A 5uunB-3g9qA:
undetectable		 5uunB-3g9qA:
21.66