SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2
(Homo
sapiens) 		4 / 7 THR A  89
HIS A  42
THR A 126
ILE A 128
 None
 0.99A 1gtnJ-3g9vA:
undetectable
1gtnK-3g9vA:
undetectable		 1gtnJ-3g9vA:
16.91
1gtnK-3g9vA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2
(Homo
sapiens) 		3 / 3 LEU A 170
TYR A 212
GLN A 213
 None
 0.64A 2wekA-3g9vA:
undetectable		 2wekA-3g9vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2
(Homo
sapiens) 		5 / 12 ASN A  40
ILE A 145
TYR A 171
GLU A 164
ILE A 163
 None
 1.49A 3q5pA-3g9vA:
undetectable		 3q5pA-3g9vA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2
(Homo
sapiens) 		4 / 6 ASN A 150
TYR A 171
GLU A 164
ILE A 163
 None
 1.07A 3q5sA-3g9vA:
undetectable		 3q5sA-3g9vA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2
(Homo
sapiens) 		4 / 6 VAL A 144
ALA A 193
VAL A 173
TYR A 171
 None
 0.91A 5i8fA-3g9vA:
undetectable		 5i8fA-3g9vA:
20.61