SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3g9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3g9w TALIN-2
(Mus
musculus) 		5 / 12 PHE A 261
LEU A 262
ALA A 245
HIS A 286
HIS A 252
 None
 1.33A 1a4lB-3g9wA:
undetectable		 1a4lB-3g9wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3g9w TALIN-2
(Mus
musculus) 		5 / 11 ALA A 363
VAL A 359
GLY A 388
ILE A 391
VAL A 340
 None
 1.20A 2uxpB-3g9wA:
undetectable		 2uxpB-3g9wA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3g9w TALIN-2
(Mus
musculus) 		4 / 7 SER A 382
ALA A 363
SER A 368
THR A 370
 None
 0.73A 3cfqA-3g9wA:
undetectable
3cfqB-3g9wA:
undetectable		 3cfqA-3g9wA:
19.42
3cfqB-3g9wA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3g9w TALIN-2
(Mus
musculus) 		3 / 3 LYS A 319
PRO A 330
LYS A 327
 None
 1.37A 4dv7L-3g9wA:
undetectable		 4dv7L-3g9wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3g9w TALIN-2
(Mus
musculus) 		4 / 7 ALA A 363
SER A 368
THR A 370
SER A 382
 None
 0.69A 4ikjA-3g9wA:
undetectable
4ikjB-3g9wA:
undetectable		 4ikjA-3g9wA:
20.48
4ikjB-3g9wA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3g9w TALIN-2
(Mus
musculus) 		4 / 7 SER A 382
ALA A 363
SER A 368
THR A 370
 None
 0.67A 4ikkA-3g9wA:
undetectable
4ikkB-3g9wA:
undetectable		 4ikkA-3g9wA:
20.48
4ikkB-3g9wA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3g9w TALIN-2
(Mus
musculus) 		4 / 7 ALA A 363
SER A 368
THR A 370
SER A 382
 None
 0.64A 4iklA-3g9wA:
undetectable
4iklB-3g9wA:
undetectable		 4iklA-3g9wA:
20.48
4iklB-3g9wA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3g9w TALIN-2
(Mus
musculus) 		4 / 8 SER A 382
ALA A 363
SER A 368
THR A 370
 None
 0.64A 4iklA-3g9wA:
undetectable
4iklB-3g9wA:
undetectable		 4iklA-3g9wA:
20.48
4iklB-3g9wA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3g9w TALIN-2
(Mus
musculus) 		5 / 12 GLY A 290
ALA A 297
GLN A 246
PHE A 243
HIS A 286
 None
 1.29A 4wh5A-3g9wA:
undetectable		 4wh5A-3g9wA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3g9w TALIN-2
(Mus
musculus) 		5 / 12 GLY A 290
PHE A 199
ALA A 297
GLN A 246
HIS A 286
 None
 1.38A 4wh5A-3g9wA:
undetectable		 4wh5A-3g9wA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3g9w TALIN-2
(Mus
musculus) 		5 / 12 PHE A 261
PHE A 283
ALA A 245
GLN A 246
PHE A 249
 None
 1.08A 4wh5A-3g9wA:
undetectable		 4wh5A-3g9wA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 3g9w TALIN-2
(Mus
musculus) 		3 / 3 CYH A 289
LYS A 287
HIS A 252
 None
 1.14A 5js5A-3g9wA:
undetectable		 5js5A-3g9wA:
19.20