SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ga2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		5 / 12 ARG A 214
LEU A 215
GLY A 117
GLY A 127
LEU A 148
 None
 1.06A 3ku1G-3ga2A:
undetectable		 3ku1G-3ga2A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		5 / 12 ILE A 143
GLY A  44
ILE A  65
ASP A 223
ALA A 222
 None
 1.19A 3uj7A-3ga2A:
undetectable		 3uj7A-3ga2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		5 / 12 ILE A 143
GLY A  44
ILE A  65
ASP A 223
ALA A 222
 None
 1.18A 3uj7B-3ga2A:
undetectable		 3uj7B-3ga2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		4 / 5 ILE A 170
ASN A 124
TYR A 123
ILE A 150
 None
 1.08A 4jtpA-3ga2A:
undetectable		 4jtpA-3ga2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		5 / 12 ALA A 132
CYH A 192
GLY A 119
GLY A 127
LEU A 190
 None
 1.14A 4n48B-3ga2A:
undetectable		 4n48B-3ga2A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		3 / 3 VAL A   6
LYS A   2
MET A   1
 None
 0.89A 5nknA-3ga2A:
undetectable		 5nknA-3ga2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		5 / 12 PHE A 189
LEU A 148
SER A 191
GLY A 119
GLY A 117
 None
 1.28A 5o4yD-3ga2A:
undetectable
5o4yE-3ga2A:
undetectable		 5o4yD-3ga2A:
3.66
5o4yE-3ga2A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3ga2 ENDONUCLEASE V
(Bacillus
subtilis) 		3 / 3 ARG A  94
ILE A  82
SER A  83
 None
 0.78A 5zw2A-3ga2A:
undetectable		 5zw2A-3ga2A:
22.36