SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ga7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 8 HIS A 292
GLY A 210
LEU A 264
ASP A 262
 SEP  A 165 ( 3.9A)
None
None
None
 0.66A 1aegA-3ga7A:
undetectable		 1aegA-3ga7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 8 HIS A 292
GLY A 215
GLY A 210
LEU A 264
 SEP  A 165 ( 3.9A)
None
None
None
 0.66A 1aegA-3ga7A:
undetectable		 1aegA-3ga7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 9 ALA A 171
LEU A 193
LEU A 192
ILE A 106
HIS A 103
 None
 1.50A 1ereA-3ga7A:
undetectable		 1ereA-3ga7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 9 ALA A 171
LEU A 193
LEU A 192
ILE A 106
HIS A 103
 None
 1.49A 1ereC-3ga7A:
undetectable		 1ereC-3ga7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 8 ALA A 166
LEU A  90
ALA A 134
THR A 138
 SEP  A 165 ( 3.2A)
None
None
None
 0.90A 1ie4B-3ga7A:
undetectable
1ie4D-3ga7A:
undetectable		 1ie4B-3ga7A:
16.61
1ie4D-3ga7A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 6 ARG A 206
GLY A 199
ASP A 267
TYR A 240
 None
 1.26A 1kf6M-3ga7A:
1.4
1kf6N-3ga7A:
undetectable		 1kf6M-3ga7A:
18.48
1kf6N-3ga7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 GLY A  94
GLY A  93
ASP A 222
ASP A 202
ARG A 207
 SEP  A 165 ( 3.5A)
SEP  A 165 ( 3.6A)
None
None
None
 0.84A 1sqfA-3ga7A:
2.9		 1sqfA-3ga7A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 5 TYR A 240
TYR A 131
ILE A 135
GLY A 199
 None
 1.05A 2du8G-3ga7A:
undetectable		 2du8G-3ga7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 8 GLY A  93
GLY A  94
ALA A 166
HIS A 292
 SEP  A 165 ( 3.6A)
SEP  A 165 ( 3.5A)
SEP  A 165 ( 3.2A)
SEP  A 165 ( 3.9A)
 0.24A 2ha4A-3ga7A:
17.9		 2ha4A-3ga7A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 GLY A  93
GLY A  94
ALA A 166
HIS A 292
 SEP  A 165 ( 3.6A)
SEP  A 165 ( 3.5A)
SEP  A 165 ( 3.2A)
SEP  A 165 ( 3.9A)
 0.21A 2ha4B-3ga7A:
18.4		 2ha4B-3ga7A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 ASP A  71
THR A  73
ILE A 121
PHE A 145
 None
 1.26A 2jc9A-3ga7A:
undetectable		 2jc9A-3ga7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 ALA A 293
TYR A 195
MET A 301
HIS A 296
 None
SEP  A 165 ( 4.6A)
None
None
 1.39A 2pncA-3ga7A:
undetectable		 2pncA-3ga7A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		3 / 3 LEU A  46
TYR A  43
GLN A  42
 None
 0.74A 2wekA-3ga7A:
3.5		 2wekA-3ga7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 LEU A 100
THR A 102
ASP A 122
LEU A 125
GLY A  93
 None
None
None
None
SEP  A 165 ( 3.6A)
 1.32A 3g1uB-3ga7A:
5.2		 3g1uB-3ga7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 LEU A 100
THR A 102
ASP A 122
LEU A 125
GLY A  93
 None
None
None
None
SEP  A 165 ( 3.6A)
 1.33A 3g1uC-3ga7A:
undetectable		 3g1uC-3ga7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 LEU A 100
THR A 102
ASP A 122
LEU A 125
GLY A  93
 None
None
None
None
SEP  A 165 ( 3.6A)
 1.32A 3g1uD-3ga7A:
5.5		 3g1uD-3ga7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 ALA A 168
GLY A  94
GLY A  93
ASP A 267
ASP A 164
 SEP  A 165 ( 3.3A)
SEP  A 165 ( 3.5A)
SEP  A 165 ( 3.6A)
None
SEP  A 165 ( 4.4A)
 1.06A 3m6vA-3ga7A:
2.7		 3m6vA-3ga7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 ALA A 168
GLY A  94
GLY A  93
ASP A 267
ASP A 164
 SEP  A 165 ( 3.3A)
SEP  A 165 ( 3.5A)
SEP  A 165 ( 3.6A)
None
SEP  A 165 ( 4.4A)
 1.05A 3m6vB-3ga7A:
undetectable		 3m6vB-3ga7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 GLY A 115
GLN A  80
LEU A 154
ILE A 189
PHE A 315
 None
 1.37A 3mnpA-3ga7A:
undetectable		 3mnpA-3ga7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 GLY A  93
GLY A  94
LEU A 221
HIS A 292
 SEP  A 165 ( 3.6A)
SEP  A 165 ( 3.5A)
None
SEP  A 165 ( 3.9A)
 0.55A 3o9mA-3ga7A:
18.2		 3o9mA-3ga7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 6 GLY A  93
GLY A  94
LEU A 221
HIS A 292
 SEP  A 165 ( 3.6A)
SEP  A 165 ( 3.5A)
None
SEP  A 165 ( 3.9A)
 0.55A 3o9mB-3ga7A:
18.4		 3o9mB-3ga7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		3 / 3 ARG A  75
MET A 107
ARG A 108
 None
 1.42A 3uvvA-3ga7A:
undetectable		 3uvvA-3ga7A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 ALA A  85
ILE A 159
GLY A 160
ILE A 189
 None
 0.57A 4eatA-3ga7A:
3.4		 4eatA-3ga7A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 7 PHE A 294
TYR A 287
TRP A 194
PHE A 255
 None
 1.36A 4grqA-3ga7A:
undetectable
4grqC-3ga7A:
undetectable		 4grqA-3ga7A:
15.34
4grqC-3ga7A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		4 / 5 PHE A 145
TYR A 144
THR A  73
ILE A 119
 None
 1.22A 4jx1E-3ga7A:
undetectable		 4jx1E-3ga7A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 11 LEU A 176
ALA A 173
LEU A 271
GLY A 163
LEU A  90
 None
 1.25A 5dxgB-3ga7A:
undetectable		 5dxgB-3ga7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 8 TYR A 240
ILE A 135
PHE A  95
GLY A 167
LEU A 197
 None
None
None
SEP  A 165 ( 4.0A)
None
 1.48A 5esfA-3ga7A:
undetectable		 5esfA-3ga7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ga7 ACETYL ESTERASE
(Salmonella
enterica) 		5 / 12 LEU A 100
THR A 102
ASP A 122
LEU A 125
GLY A  93
 None
None
None
None
SEP  A 165 ( 3.6A)
 1.32A 6aphA-3ga7A:
4.8		 6aphA-3ga7A:
20.26