SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gaa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		3 / 3 ARG A  76
ARG A  80
ILE A  64
 None
 0.71A 1uobA-3gaaA:
undetectable		 1uobA-3gaaA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		3 / 3 TRP A 113
GLU A  20
TYR A  24
 None
 0.92A 2a3aA-3gaaA:
undetectable		 2a3aA-3gaaA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		3 / 3 PRO A 129
THR A 189
PRO A 188
 None
 0.85A 2d55C-3gaaA:
undetectable		 2d55C-3gaaA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		5 / 11 ALA A 154
ILE A 156
LEU A  30
ILE A 203
PHE A 185
 None
 1.23A 2h42A-3gaaA:
undetectable		 2h42A-3gaaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 7 ILE A 171
GLY A 168
PHE A  33
PHE A  79
 None
 1.01A 2vctD-3gaaA:
undetectable		 2vctD-3gaaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 5 ALA A 205
ALA A  44
TYR A  46
MET A  53
 None
 1.28A 3d91A-3gaaA:
undetectable		 3d91A-3gaaA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 7 VAL A  89
MET A 125
ILE A 206
ILE A 214
 None
 0.88A 3hgxA-3gaaA:
undetectable		 3hgxA-3gaaA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 7 VAL A 223
LEU A 226
ASN A 207
VAL A  41
 None
 0.76A 4e1gB-3gaaA:
undetectable		 4e1gB-3gaaA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 7 ILE A 156
ALA A 141
VAL A 142
ALA A 209
 None
 0.82A 4g77A-3gaaA:
undetectable		 4g77A-3gaaA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 7 LEU A  51
THR A  50
ILE A 203
LEU A 219
 None
 0.98A 5fxtA-3gaaA:
undetectable		 5fxtA-3gaaA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3gaa UNCHARACTERIZED
PROTEIN TA1441
(Thermoplasma
acidophilum) 		4 / 8 ILE A 124
ILE A  98
LEU A 110
THR A 109
 None
 0.68A 5og9A-3gaaA:
undetectable		 5og9A-3gaaA:
19.53