SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 3gab DNA MISMATCH REPAIR
PROTEIN MUTL
(Bacillus
subtilis) 		5 / 11 VAL A 515
GLY A 516
ALA A 567
LEU A 563
SER A 555
 None
 1.27A 2bxgA-3gabA:
2.1		 2bxgA-3gabA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3gab DNA MISMATCH REPAIR
PROTEIN MUTL
(Bacillus
subtilis) 		5 / 12 PHE A 602
ILE A 610
ASP A 594
LEU A 595
ARG A 596
 None
 1.16A 3iv6D-3gabA:
undetectable		 3iv6D-3gabA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3gab DNA MISMATCH REPAIR
PROTEIN MUTL
(Bacillus
subtilis) 		3 / 3 TYR A 440
MET A 439
ILE A 612
 None
 0.81A 4c8bB-3gabA:
undetectable		 4c8bB-3gabA:
21.73