SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 3gae PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 483
LEU A 502
LEU A 509
ILE A 505
PRO A 535
 None
 1.38A 3a50B-3gaeA:
undetectable		 3a50B-3gaeA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3gae PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 469
ASP A 713
LEU A 714
GLY A 675
 None
 0.88A 3af0A-3gaeA:
undetectable		 3af0A-3gaeA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 3gae PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 463
ASP A 712
ASP A 709
LYS A 708
 None
 1.17A 3pocB-3gaeA:
undetectable		 3pocB-3gaeA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_ACTA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3gae PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 536
LYS A 533
TYR A 556
GLU A 559
 None
 1.41A 4rvdA-3gaeA:
0.0		 4rvdA-3gaeA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_ACTA504_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3gae PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 536
LYS A 533
TYR A 556
GLU A 559
 None
 1.36A 4rvgA-3gaeA:
0.0		 4rvgA-3gaeA:
20.60