SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		3 / 3 ASP A 152
ARG A  12
ARG A 147
 GOL  A 208 (-3.4A)
FMN  A 500 (-2.7A)
None
 0.71A 2j9dA-3gagA:
2.2
2j9dC-3gagA:
2.1		 2j9dA-3gagA:
20.00
2j9dC-3gagA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		3 / 3 MET A 143
GLN A 144
ARG A 147
 None
 0.75A 5ewzB-3gagA:
undetectable		 5ewzB-3gagA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		5 / 12 ILE A 164
PHE A 161
LEU A 168
VAL A  78
VAL A 159
 None
 1.26A 5km9B-3gagA:
3.0		 5km9B-3gagA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		3 / 3 MET A 143
GLN A 144
ARG A 147
 None
 0.75A 5m35B-3gagA:
undetectable		 5m35B-3gagA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		3 / 3 MET A 143
GLN A 144
ARG A 147
 None
 0.77A 6fn9A-3gagA:
undetectable		 6fn9A-3gagA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3gag PUTATIVE NADH
DEHYDROGENASE, NADPH
NITROREDUCTASE
(Streptococcus
mutans) 		3 / 3 MET A 143
GLN A 144
ARG A 147
 None
 0.78A 6fnaB-3gagA:
undetectable		 6fnaB-3gagA:
23.46