SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gaj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	5 / 10	VAL A 41 LEU A 66 LEU A 158 TYR A 161 ALA A 127	None	1.37A	1pbcA-3gajA: undetectable	1pbcA-3gajA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_C_CHDC3271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.82A	1v54C-3gajA: 2.8 1v54J-3gajA: undetectable	1v54C-3gajA: 21.16 1v54J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_P_CHDP4271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.83A	1v54P-3gajA: 2.8 1v54W-3gajA: undetectable	1v54P-3gajA: 21.16 1v54W-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.81A	2dyrC-3gajA: 2.8 2dyrJ-3gajA: undetectable	2dyrC-3gajA: 21.16 2dyrJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.85A	2dyrP-3gajA: 2.7 2dyrW-3gajA: undetectable	2dyrP-3gajA: 21.16 2dyrW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.86A	2eikC-3gajA: 2.7 2eikJ-3gajA: undetectable	2eikC-3gajA: 21.16 2eikJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.88A	2eikP-3gajA: 2.7 2eikW-3gajA: undetectable	2eikP-3gajA: 21.16 2eikW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.84A	2eilC-3gajA: 2.8 2eilJ-3gajA: undetectable	2eilC-3gajA: 21.16 2eilJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.89A	2eimP-3gajA: 2.7 2eimW-3gajA: undetectable	2eimP-3gajA: 21.16 2eimW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PKK_A_2FAA501_2 (ADENOSINE KINASE)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 4	ALA A 166 VAL A 126 PHE A 162 THR A 44	None	1.28A	2pkkA-3gajA: undetectable	2pkkA-3gajA: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 6	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.88A	3abkP-3gajA: 2.7 3abkW-3gajA: undetectable	3abkP-3gajA: 21.16 3abkW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 8	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.81A	3ag4C-3gajA: 2.7 3ag4J-3gajA: undetectable	3ag4C-3gajA: 21.16 3ag4J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.82A	3ag4P-3gajA: 2.7 3ag4W-3gajA: undetectable	3ag4P-3gajA: 21.16 3ag4W-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.84A	3asnC-3gajA: 2.8 3asnJ-3gajA: undetectable	3asnC-3gajA: 21.16 3asnJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.82A	3asnP-3gajA: 2.8 3asnW-3gajA: undetectable	3asnP-3gajA: 21.16 3asnW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.84A	3asoP-3gajA: 2.7 3asoW-3gajA: undetectable	3asoP-3gajA: 21.16 3asoW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SOA_A_DB8A445_1 (CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 6	LEU A 59 VAL A 41 PHE A 162 PHE A 154	None	1.11A	3soaA-3gajA: 2.0	3soaA-3gajA: 16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 6	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.78A	3wg7C-3gajA: 2.8 3wg7J-3gajA: undetectable	3wg7C-3gajA: 21.16 3wg7J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 6	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	1.02A	3wg7P-3gajA: 2.7 3wg7W-3gajA: undetectable	3wg7P-3gajA: 21.16 3wg7W-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.83A	3x2qC-3gajA: 2.7 3x2qJ-3gajA: undetectable	3x2qC-3gajA: 21.16 3x2qJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.95A	3x2qP-3gajA: 2.7 3x2qW-3gajA: undetectable	3x2qP-3gajA: 21.16 3x2qW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_C_STRC601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 5	ILE A 113 ARG A 132 ASP A 160 VAL A 106	None MG A 183 ( 4.6A) MG A 183 ( 4.5A) None	0.92A	4nkxC-3gajA: undetectable	4nkxC-3gajA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_D_STRD601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 5	ILE A 113 ARG A 132 ASP A 160 VAL A 106	None MG A 183 ( 4.6A) MG A 183 ( 4.5A) None	0.91A	4nkxD-3gajA: undetectable	4nkxD-3gajA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.82A	5b1aC-3gajA: 2.8 5b1aJ-3gajA: undetectable	5b1aC-3gajA: 21.16 5b1aJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.84A	5b1aP-3gajA: 2.8 5b1aW-3gajA: undetectable	5b1aP-3gajA: 21.16 5b1aW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.80A	5b1bP-3gajA: 2.8 5b1bW-3gajA: undetectable	5b1bP-3gajA: 21.16 5b1bW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	1.00A	5b3sC-3gajA: 2.7 5b3sJ-3gajA: undetectable	5b3sC-3gajA: 21.16 5b3sJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.82A	5iy5C-3gajA: 2.7 5iy5J-3gajA: undetectable	5iy5C-3gajA: 21.16 5iy5J-3gajA: 13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 5	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.88A	5x19C-3gajA: 2.7 5x19J-3gajA: undetectable	5x19C-3gajA: 21.16 5x19J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_P_CHDP304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.81A	5x1fP-3gajA: 2.7 5x1fW-3gajA: undetectable	5x1fP-3gajA: 21.16 5x1fW-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.83A	5z84C-3gajA: 2.7 5z84J-3gajA: undetectable	5z84C-3gajA: 21.16 5z84J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.83A	5z85C-3gajA: 2.7 5z85J-3gajA: undetectable	5z85C-3gajA: 21.16 5z85J-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.80A	5zcoC-3gajA: 2.7 5zcoJ-3gajA: undetectable	5zcoC-3gajA: 21.16 5zcoJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.81A	5zcqC-3gajA: 2.8 5zcqJ-3gajA: undetectable	5zcqC-3gajA: 21.16 5zcqJ-3gajA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3gaj	COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN (Lactobacillus reuteri)	4 / 7	LEU A 95 PHE A 154 LEU A 158 PHE A 162	None	0.84A	5zcqP-3gajA: 2.7 5zcqW-3gajA: undetectable	5zcqP-3gajA: 21.16 5zcqW-3gajA: 14.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PBC_A_BHAA396_0","P-HYDROXYBENZOATE HYDROXYLASE","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",5,"VAL A  41;LEU A  66;LEU A 158;TYR A 161;ALA A 127","None","1.37A","1pbcA-3gajA:undetectable","1pbcA-3gajA:20.63"],["1V54_C_CHDC3271_0","CYTOCHROME C OXIDASE POLYPEPTIDE III;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.82A","1v54C-3gajA:2.8;1v54J-3gajA:undetectable","1v54C-3gajA:21.16;1v54J-3gajA:14.52"],["1V54_P_CHDP4271_0","CYTOCHROME C OXIDASE POLYPEPTIDE III;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.83A","1v54P-3gajA:2.8;1v54W-3gajA:undetectable","1v54P-3gajA:21.16;1v54W-3gajA:14.52"],["2DYR_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.81A","2dyrC-3gajA:2.8;2dyrJ-3gajA:undetectable","2dyrC-3gajA:21.16;2dyrJ-3gajA:14.52"],["2DYR_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.85A","2dyrP-3gajA:2.7;2dyrW-3gajA:undetectable","2dyrP-3gajA:21.16;2dyrW-3gajA:14.52"],["2EIK_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.86A","2eikC-3gajA:2.7;2eikJ-3gajA:undetectable","2eikC-3gajA:21.16;2eikJ-3gajA:14.52"],["2EIK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.88A","2eikP-3gajA:2.7;2eikW-3gajA:undetectable","2eikP-3gajA:21.16;2eikW-3gajA:14.52"],["2EIL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.84A","2eilC-3gajA:2.8;2eilJ-3gajA:undetectable","2eilC-3gajA:21.16;2eilJ-3gajA:14.52"],["2EIM_W_CHDW1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.89A","2eimP-3gajA:2.7;2eimW-3gajA:undetectable","2eimP-3gajA:21.16;2eimW-3gajA:14.52"],["2PKK_A_2FAA501_2","ADENOSINE KINASE","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"ALA A 166;VAL A 126;PHE A 162;THR A  44","None","1.28A","2pkkA-3gajA:undetectable","2pkkA-3gajA:20.12"],["3ABK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.88A","3abkP-3gajA:2.7;3abkW-3gajA:undetectable","3abkP-3gajA:21.16;3abkW-3gajA:14.52"],["3AG4_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.81A","3ag4C-3gajA:2.7;3ag4J-3gajA:undetectable","3ag4C-3gajA:21.16;3ag4J-3gajA:14.52"],["3AG4_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.82A","3ag4P-3gajA:2.7;3ag4W-3gajA:undetectable","3ag4P-3gajA:21.16;3ag4W-3gajA:14.52"],["3ASN_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.84A","3asnC-3gajA:2.8;3asnJ-3gajA:undetectable","3asnC-3gajA:21.16;3asnJ-3gajA:14.52"],["3ASN_P_CHDP1271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.82A","3asnP-3gajA:2.8;3asnW-3gajA:undetectable","3asnP-3gajA:21.16;3asnW-3gajA:14.52"],["3ASO_P_CHDP1271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.84A","3asoP-3gajA:2.7;3asoW-3gajA:undetectable","3asoP-3gajA:21.16;3asoW-3gajA:14.52"],["3SOA_A_DB8A445_1","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  59;VAL A  41;PHE A 162;PHE A 154","None","1.11A","3soaA-3gajA:2.0","3soaA-3gajA:16.17"],["3WG7_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.78A","3wg7C-3gajA:2.8;3wg7J-3gajA:undetectable","3wg7C-3gajA:21.16;3wg7J-3gajA:14.52"],["3WG7_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","1.02A","3wg7P-3gajA:2.7;3wg7W-3gajA:undetectable","3wg7P-3gajA:21.16;3wg7W-3gajA:14.52"],["3X2Q_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.83A","3x2qC-3gajA:2.7;3x2qJ-3gajA:undetectable","3x2qC-3gajA:21.16;3x2qJ-3gajA:14.52"],["3X2Q_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.95A","3x2qP-3gajA:2.7;3x2qW-3gajA:undetectable","3x2qP-3gajA:21.16;3x2qW-3gajA:14.52"],["4NKX_C_STRC601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"ILE A 113;ARG A 132;ASP A 160;VAL A 106","None; MG A 183 ( 4.6A); MG A 183 ( 4.5A);None","0.92A","4nkxC-3gajA:undetectable","4nkxC-3gajA:18.94"],["4NKX_D_STRD601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"ILE A 113;ARG A 132;ASP A 160;VAL A 106","None; MG A 183 ( 4.6A); MG A 183 ( 4.5A);None","0.91A","4nkxD-3gajA:undetectable","4nkxD-3gajA:18.94"],["5B1A_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.82A","5b1aC-3gajA:2.8;5b1aJ-3gajA:undetectable","5b1aC-3gajA:21.16;5b1aJ-3gajA:14.52"],["5B1A_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.84A","5b1aP-3gajA:2.8;5b1aW-3gajA:undetectable","5b1aP-3gajA:21.16;5b1aW-3gajA:14.52"],["5B1B_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.80A","5b1bP-3gajA:2.8;5b1bW-3gajA:undetectable","5b1bP-3gajA:21.16;5b1bW-3gajA:14.52"],["5B3S_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","1.00A","5b3sC-3gajA:2.7;5b3sJ-3gajA:undetectable","5b3sC-3gajA:21.16;5b3sJ-3gajA:14.52"],["5IY5_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.82A","5iy5C-3gajA:2.7;5iy5J-3gajA:undetectable","5iy5C-3gajA:21.16;5iy5J-3gajA:13.37"],["5X19_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.88A","5x19C-3gajA:2.7;5x19J-3gajA:undetectable","5x19C-3gajA:21.16;5x19J-3gajA:14.52"],["5X1F_P_CHDP304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.81A","5x1fP-3gajA:2.7;5x1fW-3gajA:undetectable","5x1fP-3gajA:21.16;5x1fW-3gajA:14.52"],["5Z84_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.83A","5z84C-3gajA:2.7;5z84J-3gajA:undetectable","5z84C-3gajA:21.16;5z84J-3gajA:14.52"],["5Z85_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.83A","5z85C-3gajA:2.7;5z85J-3gajA:undetectable","5z85C-3gajA:21.16;5z85J-3gajA:14.52"],["5ZCO_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.80A","5zcoC-3gajA:2.7;5zcoJ-3gajA:undetectable","5zcoC-3gajA:21.16;5zcoJ-3gajA:14.52"],["5ZCQ_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.81A","5zcqC-3gajA:2.8;5zcqJ-3gajA:undetectable","5zcqC-3gajA:21.16;5zcqJ-3gajA:14.52"],["5ZCQ_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3gaj","COBALAMIN ADENOSYLTRANSFERASE PDUO-LIKE PROTEIN","Lactobacillus reuteri",4,"LEU A  95;PHE A 154;LEU A 158;PHE A 162","None","0.84A","5zcqP-3gajA:2.7;5zcqW-3gajA:undetectable","5zcqP-3gajA:21.16;5zcqW-3gajA:14.52"]]