SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gas'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		5 / 10 GLY A  19
GLU A  79
LEU A  20
LEU A  21
ILE A  45
 None
 1.36A 3kvrB-3gasA:
undetectable		 3kvrB-3gasA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		5 / 9 GLY A  19
GLU A  79
LEU A  20
LEU A  21
ILE A  45
 None
 1.40A 3nbqA-3gasA:
undetectable		 3nbqA-3gasA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 6 GLY A 139
VAL A 113
HIS A 111
THR A 105
 None
 0.87A 3tj7A-3gasA:
undetectable
3tj7B-3gasA:
undetectable		 3tj7A-3gasA:
24.25
3tj7B-3gasA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 6 GLY A 139
VAL A 113
HIS A 111
THR A 105
 None
 0.87A 3tj7C-3gasA:
undetectable
3tj7D-3gasA:
undetectable		 3tj7C-3gasA:
24.25
3tj7D-3gasA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 6 VAL A 113
HIS A 111
THR A 105
GLY A 139
 None
 0.90A 3tj7C-3gasA:
undetectable
3tj7D-3gasA:
undetectable		 3tj7C-3gasA:
24.25
3tj7D-3gasA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		3 / 3 ASP A 183
LYS A 184
ASP A 187
 None
 0.84A 4a7tA-3gasA:
undetectable		 4a7tA-3gasA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 8 THR A 173
LEU A 213
VAL A 149
VAL A 147
 None
 0.76A 4em2A-3gasA:
undetectable		 4em2A-3gasA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 6 GLU A 132
PHE A 175
ARG A 178
TYR A 129
 None
 1.49A 4uciA-3gasA:
undetectable		 4uciA-3gasA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 7 GLU A 132
PHE A 175
ARG A 178
TYR A 129
 None
 1.48A 4uciB-3gasA:
undetectable		 4uciB-3gasA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		5 / 12 MET A   9
VAL A  38
LEU A  21
THR A  71
THR A  52
 None
 1.31A 5bykA-3gasA:
undetectable		 5bykA-3gasA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 7 VAL A 101
LEU A 213
VAL A 147
THR A 171
 None
 0.89A 5e4dA-3gasA:
undetectable
5e4dB-3gasA:
undetectable		 5e4dA-3gasA:
21.64
5e4dB-3gasA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3gas HEME OXYGENASE
(Helicobacter
pylori) 		4 / 6 ALA A 117
VAL A 101
VAL A 147
HIS A 136
 None
 1.04A 5eclA-3gasA:
undetectable		 5eclA-3gasA:
19.76