SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		7 / 12 TYR A  78
ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ARG A 433
 EDO  A8003 ( 4.4A)
None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
None
 0.80A 1dedB-3gbdA:
27.0		 1dedB-3gbdA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 11 ILE A  42
GLY A 449
GLY A  39
PHE A 446
ASP A  36
 None
 0.97A 1ho5A-3gbdA:
undetectable		 1ho5A-3gbdA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 LEU A 533
PRO A 534
LEU A 537
 None
 0.39A 1hrkA-3gbdA:
undetectable		 1hrkA-3gbdA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 0.87A 1m8eB-3gbdA:
undetectable		 1m8eB-3gbdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		8 / 12 TYR A  78
HIS A 118
PHE A 178
ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
 EDO  A8003 ( 4.4A)
EDO  A8003 (-4.8A)
EDO  A8003 ( 3.9A)
None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
 0.98A 1mxdA-3gbdA:
22.3		 1mxdA-3gbdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 0.98A 1nodB-3gbdA:
undetectable		 1nodB-3gbdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 ASN A 343
HIS A 349
PHE A 350
TRP A 312
 None
None
None
EDO  A8008 (-4.0A)
 1.49A 1tdnA-3gbdA:
undetectable		 1tdnA-3gbdA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 PHE A 317
PHE A 524
TYR A 509
TYR A 496
 None
EDO  A8008 ( 4.8A)
None
None
 1.21A 2aoxA-3gbdA:
undetectable		 2aoxA-3gbdA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 6 TYR A  78
ASP A  75
PHE A 178
THR A 215
 EDO  A8003 ( 4.4A)
EDO  A8003 (-2.8A)
EDO  A8003 ( 3.9A)
EDO  A8001 ( 4.2A)
 1.16A 2dttB-3gbdA:
undetectable
2dttC-3gbdA:
undetectable		 2dttB-3gbdA:
11.89
2dttC-3gbdA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 0.99A 2nodB-3gbdA:
undetectable		 2nodB-3gbdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 TYR A 155
PRO A 156
TYR A 177
HIS A 176
 None
 1.26A 2ombC-3gbdA:
undetectable
2ombD-3gbdA:
undetectable		 2ombC-3gbdA:
15.96
2ombD-3gbdA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 LEU A 533
PRO A 534
LEU A 537
 None
 0.63A 2po5B-3gbdA:
undetectable		 2po5B-3gbdA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 LEU A 533
PRO A 534
LEU A 537
 None
 0.44A 2qd5B-3gbdA:
undetectable		 2qd5B-3gbdA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 GLY A 271
THR A 241
PHE A 178
PHE A 159
 None
None
EDO  A8003 ( 3.9A)
None
 1.04A 2qx4A-3gbdA:
undetectable
2qx4B-3gbdA:
undetectable		 2qx4A-3gbdA:
16.08
2qx4B-3gbdA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 LEU A 296
LEU A 338
PHE A 336
TYR A 509
 None
 0.96A 2vq5B-3gbdA:
undetectable		 2vq5B-3gbdA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 4 GLU A 401
ARG A 429
ASN A 343
ASP A 342
 EDO  A8002 (-3.3A)
EDO  A8003 ( 3.2A)
None
EDO  A8002 ( 3.5A)
 1.40A 2zq9A-3gbdA:
undetectable		 2zq9A-3gbdA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.74A 3aicA-3gbdA:
4.6		 3aicA-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.76A 3aicB-3gbdA:
3.3		 3aicB-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		7 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
TYR A  78
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
EDO  A8003 ( 4.4A)
 0.72A 3aicC-3gbdA:
7.5		 3aicC-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
GLU A 268
HIS A 341
ASP A 342
TYR A  78
GLN A 182
 None
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 ( 4.4A)
None
 1.03A 3aicC-3gbdA:
7.5		 3aicC-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.82A 3aicD-3gbdA:
4.3		 3aicD-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.80A 3aicE-3gbdA:
7.7		 3aicE-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.80A 3aicF-3gbdA:
4.3		 3aicF-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.77A 3aicG-3gbdA:
7.8		 3aicG-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		6 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
ASP A  75
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
EDO  A8003 (-2.8A)
 0.78A 3aicH-3gbdA:
4.2		 3aicH-3gbdA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 LEU A 185
ILE A 116
PHE A 213
ARG A 193
 None
 0.76A 3b9lA-3gbdA:
undetectable		 3b9lA-3gbdA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 5 PRO A  67
ILE A  65
PRO A  31
TYR A  30
 None
 1.00A 3d9lA-3gbdA:
undetectable
3d9lY-3gbdA:
undetectable		 3d9lA-3gbdA:
12.72
3d9lY-3gbdA:
4.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 0.85A 3e68A-3gbdA:
undetectable		 3e68A-3gbdA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 0.89A 3e6tB-3gbdA:
undetectable		 3e6tB-3gbdA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 ARG A 485
ILE A 290
TRP A 333
 None
 1.01A 3e7iB-3gbdA:
undetectable		 3e7iB-3gbdA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 11 GLY A  59
ASP A  61
ILE A 484
THR A 369
ILE A 378
 None
 0.93A 3ekxA-3gbdA:
undetectable		 3ekxA-3gbdA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 ILE A 488
GLY A 494
TYR A 509
VAL A 520
 None
 0.92A 3elzA-3gbdA:
undetectable		 3elzA-3gbdA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 GLU A 124
ASP A  82
ASP A 195
 None
 0.67A 3jb2A-3gbdA:
undetectable		 3jb2A-3gbdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 PHE A 377
ALA A 374
PHE A 292
ALA A 291
 None
 1.12A 3t3sE-3gbdA:
undetectable		 3t3sE-3gbdA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 GLN A 422
THR A 427
ASN A 423
 None
 0.64A 3v4tE-3gbdA:
undetectable		 3v4tE-3gbdA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 LEU A 533
PRO A 534
LEU A 537
 None
 0.35A 3w1wB-3gbdA:
undetectable		 3w1wB-3gbdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 TRP A 357
VAL A 347
TRP A 564
 None
 1.11A 3zq8C-3gbdA:
undetectable
3zq8D-3gbdA:
undetectable		 3zq8C-3gbdA:
2.19
3zq8D-3gbdA:
2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 6 PHE A 524
ALA A 364
LEU A 368
THR A 367
 EDO  A8008 ( 4.8A)
None
None
None
 0.98A 4dtzA-3gbdA:
undetectable		 4dtzA-3gbdA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JI8_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 LYS A  22
LYS A  16
TRP A  21
 None
 1.10A 4ji8L-3gbdA:
0.0		 4ji8L-3gbdA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 PRO A  72
ASP A  79
ALA A 179
SER A 120
 None
 0.98A 4k0bB-3gbdA:
undetectable		 4k0bB-3gbdA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 PRO A  72
ASP A  79
ALA A 179
SER A 120
 None
 0.98A 4l7iB-3gbdA:
undetectable		 4l7iB-3gbdA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 4 ASN A  73
GLY A  77
ASP A  97
ASP A  70
 None
 1.23A 4n49A-3gbdA:
1.1		 4n49A-3gbdA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 MET A 253
VAL A 250
ILE A 116
PHE A 294
ALA A 217
 None
 1.06A 4o1zB-3gbdA:
undetectable		 4o1zB-3gbdA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 VAL A 402
SER A 157
PHE A 159
ASP A  75
GLY A 160
 None
None
None
EDO  A8003 (-2.8A)
EDO  A8004 (-3.7A)
 1.49A 4pevA-3gbdA:
1.3		 4pevA-3gbdA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 TYR A 240
PHE A 236
GLY A 160
ILE A 400
 None
EDO  A8004 (-4.8A)
EDO  A8004 (-3.7A)
None
 0.90A 4qoiA-3gbdA:
undetectable
4qoiB-3gbdA:
undetectable		 4qoiA-3gbdA:
16.08
4qoiB-3gbdA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 ARG A 212
ASP A 214
GLU A 268
HIS A 341
ASP A 342
 None
EDO  A8003 ( 2.7A)
EDO  A8001 (-3.1A)
None
EDO  A8002 ( 3.5A)
 0.47A 5csyB-3gbdA:
17.5		 5csyB-3gbdA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		3 / 3 GLY A  41
ASP A  36
ASN A  46
 None
 0.58A 5jglA-3gbdA:
undetectable		 5jglA-3gbdA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 VAL A 521
LEU A 561
ALA A 508
LEU A 571
 None
 0.65A 5jq7A-3gbdA:
undetectable		 5jq7A-3gbdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 4 VAL A 468
LEU A  58
ASN A 463
ASP A 439
 EDO  A8005 (-4.6A)
None
None
None
 1.35A 5vcyA-3gbdA:
2.4		 5vcyA-3gbdA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 ASN A  73
GLY A  77
GLY A  43
SER A  33
ILE A  42
 None
 1.17A 5vooD-3gbdA:
10.2		 5vooD-3gbdA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 ASN A  73
GLY A  77
GLY A  43
SER A  33
ILE A  42
 None
 1.17A 5vooF-3gbdA:
9.5		 5vooF-3gbdA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 TYR A  78
HIS A 118
ASP A 214
HIS A 341
ASP A 342
 EDO  A8003 ( 4.4A)
EDO  A8003 (-4.8A)
EDO  A8003 ( 2.7A)
None
EDO  A8002 ( 3.5A)
 0.42A 6ag0A-3gbdA:
19.5		 6ag0A-3gbdA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 8 TRP A  21
TYR A 493
GLU A  23
TRP A 333
 None
 1.09A 6c71B-3gbdA:
undetectable		 6c71B-3gbdA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		5 / 12 ASP A 282
ALA A 291
GLY A 329
GLY A 332
VAL A 324
 None
 1.13A 6clxA-3gbdA:
undetectable		 6clxA-3gbdA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 TRP A 203
HIS A  68
ARG A 212
ASP A 113
 None
 1.31A 6mn4E-3gbdA:
undetectable		 6mn4E-3gbdA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM
(Serratia
plymuthica) 		4 / 7 GLY A  43
HIS A 341
ASN A  66
GLY A  77
 None
 0.95A 6n7fA-3gbdA:
undetectable		 6n7fA-3gbdA:
11.00