SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		4 / 6 LEU A  78
ALA A 187
LEU A  85
ALA A  56
 None
 0.84A 2vcvB-3gbhA:
undetectable		 2vcvB-3gbhA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		4 / 6 LEU A  78
ALA A 187
LEU A  85
ALA A  56
 None
 0.80A 2vcvK-3gbhA:
undetectable		 2vcvK-3gbhA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		5 / 12 PHE A  23
THR A 160
ASP A  35
ILE A  38
LEU A  85
 None
 1.25A 3iv6A-3gbhA:
undetectable		 3iv6A-3gbhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		5 / 12 PHE A  23
THR A 160
ASP A  35
ILE A  38
LEU A  85
 None
 1.24A 3iv6B-3gbhA:
undetectable		 3iv6B-3gbhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		5 / 12 PHE A  23
THR A 160
ASP A  35
ILE A  38
LEU A  85
 None
 1.25A 3iv6C-3gbhA:
undetectable		 3iv6C-3gbhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		3 / 3 TYR A  94
ASP A  90
ASP A 141
 None
 0.91A 3ou7B-3gbhA:
undetectable		 3ou7B-3gbhA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 3gbh NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Staphylococcus
epidermidis) 		5 / 11 ASP A  35
GLU A  36
ILE A 190
ARG A   6
THR A 152
 None
 1.40A 4urnA-3gbhA:
undetectable		 4urnA-3gbhA:
18.53