SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		4 / 4 ILE A 123
LEU A 162
VAL A 148
ILE A 197
 None
 0.72A 1fm6D-3gbjA:
undetectable		 1fm6D-3gbjA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 223
VAL A 225
VAL A 252
LEU A 314
 UNX  A   1 ( 4.6A)
None
None
None
 0.91A 2gehA-3gbjA:
undetectable		 2gehA-3gbjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		5 / 10 VAL A 146
VAL A 191
ILE A 197
LEU A  88
LEU A 126
 None
 1.40A 4jtqA-3gbjA:
undetectable		 4jtqA-3gbjA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		5 / 12 ARG A  11
GLY A  75
ALA A 117
GLY A 115
TYR A 111
 ADP  A2001 ( 3.8A)
None
None
None
ADP  A2001 (-3.5A)
 1.11A 4r29B-3gbjA:
undetectable		 4r29B-3gbjA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 103
TYR A 346
ALA A 350
SER A 250
MET A 113
 None
 1.22A 5igvA-3gbjA:
undetectable		 5igvA-3gbjA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 223
VAL A 225
VAL A 252
LEU A 314
 UNX  A   1 ( 4.6A)
None
None
None
 0.84A 5tt3F-3gbjA:
undetectable		 5tt3F-3gbjA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3gbj KIF13B PROTEIN
(Homo
sapiens) 		3 / 3 TYR A 182
LEU A 171
ASP A 163
 None
 0.75A 5zv2B-3gbjA:
undetectable		 5zv2B-3gbjA:
11.30