SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 10 ALA A 109
LEU A   8
VAL A  35
TYR A  42
ILE A   6
 None
 1.18A 1claA-3gboA:
undetectable		 1claA-3gboA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.25A 1os2A-3gboA:
10.7		 1os2A-3gboA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.22A 1os2D-3gboA:
10.7		 1os2D-3gboA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 8 GLY A 147
GLY A 112
GLY A 113
MET A 114
 None
 0.59A 1qzzA-3gboA:
undetectable		 1qzzA-3gboA:
18.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 10 THR A 137
HIS A 140
GLU A 141
HIS A 144
ALA A 165
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
None
 1.20A 1r55A-3gboA:
31.6		 1r55A-3gboA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 10 THR A 137
HIS A 140
GLU A 141
HIS A 144
HIS A 150
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.20A 1r55A-3gboA:
31.6		 1r55A-3gboA:
37.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.22A 1uttA-3gboA:
11.0		 1uttA-3gboA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.26A 1utzA-3gboA:
10.9		 1utzA-3gboA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.26A 1utzB-3gboA:
11.0		 1utzB-3gboA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 6 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.21A 1y93A-3gboA:
11.1		 1y93A-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.18A 2hu6A-3gboA:
10.9		 2hu6A-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 HIS A 140
GLU A 141
HIS A 144
HIS A 150
LEU A 168
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
None
 0.79A 2jihA-3gboA:
25.7		 2jihA-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 LEU A 168
THR A 137
HIS A 140
HIS A 144
HIS A 150
 None
None
ZN  A 302 (-3.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 1.38A 2jihA-3gboA:
25.7		 2jihA-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 THR A 137
HIS A 140
GLU A 141
HIS A 144
HIS A 150
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.26A 2jihA-3gboA:
25.7		 2jihA-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 8 HIS A 140
GLU A 141
HIS A 144
HIS A 150
LEU A 168
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
None
 0.51A 2jihB-3gboA:
25.5		 2jihB-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 8 LEU A 168
THR A 137
HIS A 140
HIS A 144
HIS A 150
 None
None
ZN  A 302 (-3.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 1.27A 2jihB-3gboA:
25.5		 2jihB-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 8 THR A 137
HIS A 140
GLU A 141
HIS A 144
HIS A 150
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.28A 2jihB-3gboA:
25.5		 2jihB-3gboA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 6 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.29A 2ow9A-3gboA:
10.4		 2ow9A-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.28A 2ow9B-3gboA:
10.2		 2ow9B-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.31A 2ozrC-3gboA:
10.0		 2ozrC-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.32A 2ozrD-3gboA:
10.2		 2ozrD-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.35A 2ozrE-3gboA:
10.2		 2ozrE-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		3 / 3 HIS A 140
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.30A 2ozrF-3gboA:
10.0		 2ozrF-3gboA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 ALA A 109
SER A 120
LEU A   8
TYR A  42
ILE A   6
 None
 1.40A 3claA-3gboA:
undetectable		 3claA-3gboA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 HIS A 140
GLU A 141
HIS A 144
HIS A 150
LEU A 168
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
None
 0.75A 3hy7A-3gboA:
26.2		 3hy7A-3gboA:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 9 THR A 137
HIS A 140
GLU A 141
HIS A 144
HIS A 150
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.22A 3hy7A-3gboA:
26.2		 3hy7A-3gboA:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		6 / 9 THR A 137
HIS A 140
GLU A 141
HIS A 144
HIS A 150
LEU A 168
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
None
 0.63A 3hy7B-3gboA:
26.0		 3hy7B-3gboA:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.26A 3kecA-3gboA:
10.4		 3kecA-3gboA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		3 / 3 HIS A 140
GLU A 141
HIS A 144
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
 0.22A 3kecB-3gboA:
10.2		 3kecB-3gboA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.21A 3likA-3gboA:
11.1		 3likA-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.22A 3lilA-3gboA:
11.1		 3lilA-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 5 ILE A 106
HIS A 140
GLU A 141
HIS A 144
HIS A 150
 None
ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 1.41A 3ljgA-3gboA:
11.1		 3ljgA-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.19A 3lkaA-3gboA:
11.0		 3lkaA-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 12 LEU A 146
ASN A 145
MET A 114
ALA A  49
ILE A 196
 None
 1.06A 3ut5D-3gboA:
undetectable		 3ut5D-3gboA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 6 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.36A 4a7bA-3gboA:
10.3		 4a7bA-3gboA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 12 LEU A 146
ASN A 145
MET A 114
ALA A  49
ILE A 196
 None
 1.01A 4x1iD-3gboA:
undetectable		 4x1iD-3gboA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		5 / 12 LEU A 146
ASN A 145
MET A 114
ALA A  49
ILE A 196
 None
 1.01A 4x1yD-3gboA:
undetectable		 4x1yD-3gboA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 LEU A 168
ILE A 163
HIS A 140
VAL A 136
 None
None
ZN  A 302 (-3.3A)
None
 1.15A 4xyzA-3gboA:
undetectable		 4xyzA-3gboA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 4 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.21A 5n5jA-3gboA:
11.1		 5n5jA-3gboA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 HIS A 140
GLU A 141
HIS A 144
HIS A 150
 ZN  A 302 (-3.3A)
ZN  A 302 ( 4.6A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.2A)
 0.23A 5n5kA-3gboA:
11.1		 5n5kA-3gboA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		3 / 3 HIS A 150
HIS A 144
HIS A 140
 ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
ZN  A 302 (-3.3A)
 0.68A 5x1fN-3gboA:
undetectable		 5x1fN-3gboA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 5 MET A 164
TYR A 187
GLY A 147
GLY A 112
 None
 1.14A 5x7pA-3gboA:
undetectable		 5x7pA-3gboA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 7 SER A 120
GLY A 113
ARG A  80
LEU A  85
 None
 1.04A 6btxA-3gboA:
undetectable		 6btxA-3gboA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I
(Bothrops
moojeni) 		4 / 6 MET A 125
THR A  97
LEU A  96
THR A  72
 None
 1.09A 6mvxA-3gboA:
undetectable
6mvxB-3gboA:
undetectable
6mvxC-3gboA:
undetectable		 6mvxA-3gboA:
21.81
6mvxB-3gboA:
21.81
6mvxC-3gboA:
21.81