SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 5 ALA A  31
ALA A 273
ALA A  62
VAL A   7
 None
 0.92A 2nyrB-3gbpA:
5.9		 2nyrB-3gbpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 LEU A  67
ALA A  98
LEU A  99
ALA A 105
 None
 0.96A 2vcvB-3gbpA:
undetectable		 2vcvB-3gbpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 LEU A  67
ALA A  98
LEU A  99
ALA A 105
 None
 0.98A 2vcvK-3gbpA:
undetectable		 2vcvK-3gbpA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 4 ASN A 210
ALA A 155
GLY A 148
THR A 180
 None
 1.35A 4bboC-3gbpA:
undetectable		 4bboC-3gbpA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 LYS A 125
GLY A 297
ALA A 237
ASP A 299
VAL A 298
 None
 1.41A 4df3A-3gbpA:
2.3		 4df3A-3gbpA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 LYS A 125
GLY A 297
ALA A 237
ASP A 299
VAL A 298
 None
 1.43A 4df3B-3gbpA:
4.4		 4df3B-3gbpA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A  16
ALA A 258
GLY A 109
VAL A 293
 BGC  A 308 (-3.6A)
None
None
None
 0.83A 4dubA-3gbpA:
undetectable		 4dubA-3gbpA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A  16
ALA A 258
GLY A 109
VAL A 293
 BGC  A 308 (-3.6A)
None
None
None
 0.79A 4dubB-3gbpA:
undetectable		 4dubB-3gbpA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 255
ALA A 237
VAL A 235
ASP A 154
ASP A  14
 None
None
None
BGC  A 308 ( 3.4A)
BGC  A 308 ( 2.5A)
 1.38A 4uuuA-3gbpA:
undetectable
4uuuB-3gbpA:
undetectable		 4uuuA-3gbpA:
19.42
4uuuB-3gbpA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 VAL A  76
LYS A  79
ALA A  80
VAL A  87
 None
 1.07A 5i8fA-3gbpA:
undetectable		 5i8fA-3gbpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3gbp GALACTOSE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 11 VAL A  68
ALA A 258
PHE A  90
GLN A  48
TYR A 107
 None
 1.16A 6dryA-3gbpA:
undetectable		 6dryA-3gbpA:
21.90