SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBM_A_CAMA517_0 (CYTOCHROME P450-CAM)	3gby	UNCHARACTERIZED PROTEIN CT1051 (Chlorobaculum tepidum)	4 / 8	VAL A 2 THR A 3 VAL A 112 ILE A 117	None	0.96A	2qbmA-3gbyA: undetectable	2qbmA-3gbyA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6V_E_RBFE201_1 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT B NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT E)	3gby	UNCHARACTERIZED PROTEIN CT1051 (Chlorobaculum tepidum)	4 / 5	HIS A 49 VAL A 48 GLU A 73 LYS A 95	None	1.13A	4p6vB-3gbyA: undetectable 4p6vE-3gbyA: undetectable	4p6vB-3gbyA: 14.50 4p6vE-3gbyA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B8I_C_FK5C201_1 (SERINE/THREONINE-PRO TEIN PHOSPHATASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3gby	UNCHARACTERIZED PROTEIN CT1051 (Chlorobaculum tepidum)	4 / 6	SER A 5 PRO A 80 PHE A 4 GLU A 82	None EPE A 127 (-3.9A) None EPE A 127 (-4.5A)	1.27A	5b8iA-3gbyA: undetectable	5b8iA-3gbyA: 15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_E_LLLE301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	3gby	UNCHARACTERIZED PROTEIN CT1051 (Chlorobaculum tepidum)	4 / 7	ARG A 107 GLU A 109 ASP A 103 GLU A 104	None	1.10A	6mn5E-3gbyA: undetectable	6mn5E-3gbyA: 21.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QBM_A_CAMA517_0","CYTOCHROME P450-CAM","3gby","UNCHARACTERIZED PROTEIN CT1051","Chlorobaculum tepidum",4,"VAL A   2;THR A   3;VAL A 112;ILE A 117","None","0.96A","2qbmA-3gbyA:undetectable","2qbmA-3gbyA:19.35"],["4P6V_E_RBFE201_1","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT B;NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT E","3gby","UNCHARACTERIZED PROTEIN CT1051","Chlorobaculum tepidum",4,"HIS A  49;VAL A  48;GLU A  73;LYS A  95","None","1.13A","4p6vB-3gbyA:undetectable;4p6vE-3gbyA:undetectable","4p6vB-3gbyA:14.50;4p6vE-3gbyA:22.66"],["5B8I_C_FK5C201_1","SERINE\/THREONINE-PROTEIN PHOSPHATASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3gby","UNCHARACTERIZED PROTEIN CT1051","Chlorobaculum tepidum",4,"SER A   5;PRO A  80;PHE A   4;GLU A  82","None;EPE A 127 (-3.9A);None;EPE A 127 (-4.5A)","1.27A","5b8iA-3gbyA:undetectable","5b8iA-3gbyA:15.00"],["6MN5_E_LLLE301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","3gby","UNCHARACTERIZED PROTEIN CT1051","Chlorobaculum tepidum",4,"ARG A 107;GLU A 109;ASP A 103;GLU A 104","None","1.10A","6mn5E-3gbyA:undetectable","6mn5E-3gbyA:21.54"]]