SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gcg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		5 / 12 THR B 190
ALA B 193
GLU B 196
LEU B 195
LEU B  91
 None
 1.26A 1errA-3gcgB:
undetectable		 1errA-3gcgB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		5 / 9 GLN B  57
GLY B  52
ASN B 177
ILE B 173
VAL B 169
 None
 1.29A 2drdA-3gcgB:
undetectable		 2drdA-3gcgB:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		4 / 6 ARG B  96
GLN B 171
GLU B 167
TYR B  82
 None
 1.42A 2ya7C-3gcgB:
undetectable		 2ya7C-3gcgB:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		4 / 5 LEU B  59
ALA B  61
THR B  55
PHE B 134
 None
 1.34A 3vasB-3gcgB:
undetectable		 3vasB-3gcgB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		5 / 12 THR B 190
ALA B 193
GLU B 196
LEU B 195
LEU B  91
 None
 1.22A 4xi3A-3gcgB:
undetectable		 4xi3A-3gcgB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		5 / 12 THR B 190
ALA B 193
GLU B 196
LEU B 195
LEU B  91
 None
 1.22A 4xi3D-3gcgB:
undetectable		 4xi3D-3gcgB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3gcg L0028 (MITOCHONDRIA
ASSOCIATED PROTEIN)
(Escherichia
coli) 		3 / 3 ASN B  56
VAL B 169
HIS B  51
 None
 0.68A 6a5yD-3gcgB:
undetectable		 6a5yD-3gcgB:
18.79