SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gdc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 4 THR A  25
LEU A  28
LEU A 220
GLN A 259
 None
 1.13A 1fbmA-3gdcA:
undetectable		 1fbmA-3gdcA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 4 ASP A  49
HIS A  90
ARG A  35
GLU A  47
 None
 1.41A 1lqtA-3gdcA:
undetectable		 1lqtA-3gdcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 4 ASP A  49
HIS A  90
ARG A  35
GLU A  47
 None
 1.28A 1lquA-3gdcA:
0.0		 1lquA-3gdcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 1.00A 1wmqA-3gdcA:
undetectable		 1wmqA-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 1.00A 1wmqB-3gdcA:
undetectable		 1wmqB-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 0.99A 1wpuA-3gdcA:
undetectable		 1wpuA-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 0.99A 1wpuB-3gdcA:
undetectable		 1wpuB-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 0.94A 1wrqA-3gdcA:
undetectable		 1wrqA-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A 169
ILE A 266
GLY A 265
HIS A 219
 None
 0.98A 1wrqB-3gdcA:
undetectable		 1wrqB-3gdcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		3 / 3 ASP A 173
GLU A 164
TYR A 242
 None
 0.77A 1wsvA-3gdcA:
undetectable		 1wsvA-3gdcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 HIS A 219
TYR A 241
ARG A 264
GLY A 245
 None
 1.29A 2i30A-3gdcA:
undetectable		 2i30A-3gdcA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 7 ILE A 266
GLY A 265
ARG A 264
PHE A 137
 None
 1.00A 2vctD-3gdcA:
undetectable		 2vctD-3gdcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 10 ILE A 162
GLY A 138
TRP A  80
GLU A 164
ALA A 172
 None
 1.35A 2yk1H-3gdcA:
1.7
2yk1L-3gdcA:
2.5		 2yk1H-3gdcA:
22.00
2yk1L-3gdcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A  99
HIS A 152
HIS A  97
ASP A  54
 CU  A 301 (-3.1A)
CU  A 301 (-3.2A)
None
None
 1.13A 3c0zA-3gdcA:
undetectable		 3c0zA-3gdcA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 HIS A  99
HIS A 152
HIS A  97
ASP A  54
 CU  A 301 (-3.1A)
CU  A 301 (-3.2A)
None
None
 1.15A 3c0zC-3gdcA:
undetectable		 3c0zC-3gdcA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		3 / 3 ARG A  82
GLU A 175
ASP A 173
 None
 0.90A 3g2oA-3gdcA:
undetectable		 3g2oA-3gdcA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 10 GLY A  76
TRP A  68
ILE A  50
ASN A  71
GLY A  72
 None
 1.29A 3km6A-3gdcA:
undetectable		 3km6A-3gdcA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		3 / 3 HIS A 280
HIS A 233
HIS A 235
 CU  A 304 (-3.1A)
CU  A 302 (-3.0A)
CU  A 304 ( 3.1A)
 0.79A 3mihA-3gdcA:
undetectable		 3mihA-3gdcA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		3 / 3 HIS A 280
HIS A 235
MET A 278
 CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
CU  A 304 ( 3.9A)
 0.51A 3mihA-3gdcA:
undetectable		 3mihA-3gdcA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A  99
CYH A 144
HIS A 152
LEU A 157
 CU  A 301 (-3.1A)
CU  A 301 (-2.1A)
CU  A 301 (-3.2A)
CU  A 301 (-4.6A)
 0.71A 3qpkA-3gdcA:
22.8		 3qpkA-3gdcA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 7 ASN A 181
LEU A 224
GLY A 290
TYR A 194
 None
 0.79A 4cp3A-3gdcA:
undetectable
4cp3B-3gdcA:
undetectable		 4cp3A-3gdcA:
18.56
4cp3B-3gdcA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 4 VAL A 210
VAL A 216
ASN A 237
ILE A 234
 None
 1.23A 4cutA-3gdcA:
undetectable		 4cutA-3gdcA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 SER A 195
LEU A 224
LEU A 220
ASN A 191
 None
 1.18A 4n09B-3gdcA:
undetectable		 4n09B-3gdcA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 6 ARG A  33
HIS A 219
ARG A 217
ILE A 162
 None
 1.21A 5a06A-3gdcA:
undetectable		 5a06A-3gdcA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 8 ASN A  93
PRO A 124
PHE A  91
TRP A  68
 None
 1.40A 5amkA-3gdcA:
undetectable		 5amkA-3gdcA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 12 ALA A 281
GLY A 290
GLY A 293
GLU A 192
LEU A 289
 None
None
None
CA  A 401 (-2.2A)
None
 0.97A 5c0oH-3gdcA:
undetectable		 5c0oH-3gdcA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 8 LEU A 269
PHE A 239
PHE A 232
PRO A 250
 None
 1.05A 5m0oC-3gdcA:
undetectable		 5m0oC-3gdcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mhwA-3gdcA:
24.1		 5mhwA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mhxA-3gdcA:
24.1		 5mhxA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mhyA-3gdcA:
24.1		 5mhyA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mhzA-3gdcA:
24.2		 5mhzA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mi1A-3gdcA:
24.1		 5mi1A-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mi2A-3gdcA:
24.1		 5mi2A-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5miaA-3gdcA:
24.1		 5miaA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mibA-3gdcA:
24.1		 5mibA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5micA-3gdcA:
24.1		 5micA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5midA-3gdcA:
13.5		 5midA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.95A 5mieA-3gdcA:
24.1		 5mieA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 5 HIS A 282
HIS A 233
HIS A 280
HIS A 235
 None
CU  A 302 (-3.0A)
CU  A 304 (-3.1A)
CU  A 304 ( 3.1A)
 0.94A 5migA-3gdcA:
24.1		 5migA-3gdcA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 11 PRO A 207
ILE A 234
PHE A 271
MET A 178
LEU A 220
 None
 1.18A 5tiyA-3gdcA:
undetectable		 5tiyA-3gdcA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		4 / 7 GLU A 175
PHE A  31
GLY A 265
TYR A 242
 None
 1.00A 5uxdA-3gdcA:
undetectable		 5uxdA-3gdcA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 12 PRO A 207
ILE A 234
PHE A 271
MET A 178
LEU A 220
 None
 1.22A 6b52A-3gdcA:
undetectable		 6b52A-3gdcA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 12 GLY A 138
ILE A 162
HIS A 104
LEU A 141
GLY A 160
 None
None
CU  A 303 ( 3.2A)
None
None
 1.48A 6bp4B-3gdcA:
undetectable		 6bp4B-3gdcA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 12 GLY A 245
ILE A 162
HIS A 104
LEU A 141
GLY A 160
 None
None
CU  A 303 ( 3.2A)
None
None
 1.35A 6bp4B-3gdcA:
undetectable		 6bp4B-3gdcA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3gdc MULTICOPPER OXIDASE
(Arthrobacter
sp.
FB24) 		5 / 12 GLY A 113
PHE A  57
ILE A  22
GLY A  72
THR A 100
 None
 1.20A 6e8qA-3gdcA:
undetectable		 6e8qA-3gdcA:
13.78