SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		5 / 12 TYR A 175
ILE A 157
GLY A 163
ASP A 257
ALA A 166
 None
 1.32A 1nbhC-3gdfA:
6.6		 1nbhC-3gdfA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		4 / 8 ASP A 114
SER A 115
ALA A 124
SER A 121
 None
 1.09A 4lv9A-3gdfA:
undetectable
4lv9B-3gdfA:
2.6		 4lv9A-3gdfA:
20.21
4lv9B-3gdfA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		4 / 7 ASP A 114
SER A 115
ALA A 124
SER A 121
 None
 1.09A 4lv9A-3gdfA:
undetectable
4lv9B-3gdfA:
2.6		 4lv9A-3gdfA:
20.21
4lv9B-3gdfA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		4 / 7 THR A  26
THR A 158
ALA A 159
THR A 136
 None
 0.90A 4qw0K-3gdfA:
undetectable		 4qw0K-3gdfA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		4 / 7 THR A  26
THR A 158
ALA A 159
THR A 136
 None
 0.90A 4qw0Y-3gdfA:
undetectable		 4qw0Y-3gdfA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		5 / 12 GLY A  35
ALA A  28
SER A  29
ILE A 202
SER A 203
 None
 1.23A 4rtpA-3gdfA:
5.6		 4rtpA-3gdfA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		4 / 8 ILE A  51
VAL A  49
TYR A 242
ILE A 106
 None
 0.87A 5mzrE-3gdfA:
undetectable		 5mzrE-3gdfA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		5 / 12 GLY A 153
SER A 154
GLN A  15
LEU A  16
LEU A  18
 None
 1.25A 5nwwA-3gdfA:
undetectable		 5nwwA-3gdfA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE
(Cladosporium
herbarum) 		5 / 12 GLY A  27
ALA A  28
SER A  87
GLU A  89
VAL A  95
 None
 1.17A 6bqgA-3gdfA:
undetectable		 6bqgA-3gdfA:
14.83