SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		3 / 3 VAL A 349
ALA A 348
HIS A 430
 None
 0.58A 1q23C-3gdiA:
undetectable		 1q23C-3gdiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		3 / 3 VAL A 349
ALA A 348
HIS A 430
 None
 0.63A 1q23H-3gdiA:
undetectable		 1q23H-3gdiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		3 / 3 VAL A 349
ALA A 348
HIS A 430
 None
 0.57A 1q23G-3gdiA:
undetectable		 1q23G-3gdiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		3 / 3 VAL A 349
ALA A 348
HIS A 430
 None
 0.64A 1q23L-3gdiA:
undetectable		 1q23L-3gdiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		3 / 3 VAL A 349
ALA A 348
HIS A 430
 None
 0.57A 1q23J-3gdiA:
undetectable		 1q23J-3gdiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		4 / 7 THR A 410
PHE A 391
HIS A 380
ILE A 379
 None
 0.78A 2y7wC-3gdiA:
undetectable		 2y7wC-3gdiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		5 / 12 GLY A 275
SER A 273
ARG A 271
ALA A 230
ASP A 233
 None
 1.08A 3keeA-3gdiA:
undetectable		 3keeA-3gdiA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		5 / 12 GLY A 275
SER A 273
ARG A 271
ALA A 230
ASP A 233
 None
 0.93A 3keeC-3gdiA:
undetectable		 3keeC-3gdiA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		5 / 12 GLY A 275
SER A 273
ARG A 271
ALA A 230
ASP A 233
 None
 1.07A 3keeD-3gdiA:
undetectable		 3keeD-3gdiA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		4 / 5 PHE A 228
PHE A 225
PHE A 213
PHE A 191
 None
 1.49A 3ko0F-3gdiA:
undetectable
3ko0G-3gdiA:
undetectable		 3ko0F-3gdiA:
14.53
3ko0G-3gdiA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		5 / 11 ASN A 402
SER A 317
GLY A 318
GLU A 320
THR A 400
 None
 1.33A 4xt7A-3gdiA:
undetectable		 4xt7A-3gdiA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		4 / 7 ARG A 397
ASP A 372
ILE A 396
TYR A 393
 None
 1.39A 5a06B-3gdiA:
undetectable		 5a06B-3gdiA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2
(Mus
musculus) 		4 / 4 LEU A 311
LEU A 309
SER A 206
ALA A 194
 None
 0.83A 5uunA-3gdiA:
undetectable		 5uunA-3gdiA:
22.81