SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 6 HIS A  50
GLY A  51
ALA A  26
GLU A  23
 None
 0.96A 1dmaB-3gdjA:
undetectable		 1dmaB-3gdjA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		5 / 6 ALA A  57
LYS A  60
ASP A  64
ALA A  65
LEU A  83
 None
None
None
HEM  A 142 ( 3.8A)
HEM  A 142 ( 4.6A)
 0.37A 1iwhA-3gdjA:
27.5		 1iwhA-3gdjA:
85.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 7 PHE A  43
PHE A  46
VAL A  62
HIS A  87
 HEM  A 142 (-3.9A)
HEM  A 142 (-4.7A)
HEM  A 142 ( 4.0A)
HEM  A 142 (-3.5A)
 1.01A 1lh6A-3gdjA:
13.5		 1lh6A-3gdjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 7 PHE B  42
PHE B  45
VAL B  67
HIS B  92
 HEM  B 147 (-4.0A)
None
HEM  B 147 ( 3.9A)
HEM  B 147 (-3.4A)
 0.80A 1lh6A-3gdjB:
14.0		 1lh6A-3gdjB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 5 PHE B 122
LEU B 110
VAL B 134
VAL B  11
 None
 1.18A 1t88B-3gdjB:
undetectable		 1t88B-3gdjB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 7 LEU A  29
PHE A  46
PHE A  33
LEU A 101
 None
HEM  A 142 (-4.7A)
None
HEM  A 142 (-4.5A)
 1.00A 1wrlE-3gdjA:
undetectable
1wrlF-3gdjA:
undetectable		 1wrlE-3gdjA:
23.08
1wrlF-3gdjA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		5 / 12 PHE B  71
GLY B  72
LEU B   3
LEU B  81
LEU B 114
 HEM  B 147 (-4.2A)
None
None
None
None
 1.36A 1zgyA-3gdjB:
undetectable		 1zgyA-3gdjB:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		5 / 11 ALA A  69
LEU A  76
SER A  84
LEU A 136
VAL A 135
 None
 1.08A 2bxeB-3gdjA:
undetectable		 2bxeB-3gdjA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		5 / 12 PHE A 128
LEU A 136
HIS A  87
ALA A  79
ALA A  65
 None
None
HEM  A 142 (-3.5A)
None
HEM  A 142 ( 3.8A)
 0.94A 2bxpA-3gdjA:
2.4		 2bxpA-3gdjA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		5 / 12 GLY B  83
LEU B  75
GLY B  74
LEU B  78
LEU B   3
 None
 0.94A 2nxeA-3gdjB:
undetectable		 2nxeA-3gdjB:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 4 ARG A  31
GLY A  25
GLU A  27
SER A 133
 None
 1.13A 2xctS-3gdjA:
undetectable
2xctU-3gdjA:
undetectable		 2xctS-3gdjA:
13.90
2xctU-3gdjA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 5 LEU B  28
LEU B 106
THR B  38
TRP B  37
 None
HEM  B 147 (-3.9A)
HEM  B 147 (-4.1A)
None
 1.38A 4do3A-3gdjB:
undetectable		 4do3A-3gdjB:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 5 PHE B 122
LEU B 110
VAL B 134
VAL B  11
 None
 1.16A 4l49A-3gdjB:
undetectable		 4l49A-3gdjB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 8 VAL A  96
LEU A 100
GLN B 131
VAL B 134
 None
 0.77A 4ma7A-3gdjA:
3.0		 4ma7A-3gdjA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 5 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.7A)
 0.97A 4n09C-3gdjA:
undetectable		 4n09C-3gdjA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		5 / 11 LEU B 126
HIS B  12
LEU B  14
ALA B  10
LEU B  75
 None
 1.14A 4p65C-3gdjB:
undetectable
4p65D-3gdjB:
undetectable
4p65J-3gdjB:
undetectable
4p65L-3gdjB:
undetectable		 4p65C-3gdjB:
5.63
4p65D-3gdjB:
12.26
4p65J-3gdjB:
12.26
4p65L-3gdjB:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		4 / 4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.7A)
 0.90A 5kb5A-3gdjA:
undetectable		 5kb5A-3gdjA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.23A 5qggA-3gdjB:
undetectable		 5qggA-3gdjB:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.20A 5qgoA-3gdjB:
undetectable		 5qgoA-3gdjB:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gdj HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		4 / 4 VAL B 133
VAL B 134
TYR B 130
GLN B 127
 None
 1.20A 5qgpA-3gdjB:
undetectable		 5qgpA-3gdjB:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
(Camelus
dromedarius) 		5 / 12 VAL A  62
PHE A 128
VAL A 109
LEU A 129
VAL A 132
 HEM  A 142 ( 4.0A)
None
None
None
None
 1.11A 5tudD-3gdjA:
2.5		 5tudD-3gdjA:
15.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		5 / 8 PRO A  95
THR A 134
THR A 137
TYR A 140
TRP B  37
 None
 0.70A 5x2sI-3gdjA:
26.0
5x2sJ-3gdjA:
21.7
5x2sK-3gdjA:
25.8		 5x2sI-3gdjA:
84.40
5x2sJ-3gdjA:
42.95
5x2sK-3gdjA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3gdj HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Camelus
dromedarius) 		5 / 8 PRO A  95
ALA A 130
THR A 134
THR A 137
TRP B  37
 None
 0.61A 5x2tI-3gdjA:
26.0
5x2tJ-3gdjA:
21.9
5x2tK-3gdjA:
25.9
5x2tL-3gdjA:
20.2		 5x2tI-3gdjA:
84.40
5x2tJ-3gdjA:
42.95
5x2tK-3gdjA:
84.40
5x2tL-3gdjA:
42.95