SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ge2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 3ge2 LIPOPROTEIN,
PUTATIVE
(Streptococcus
pneumoniae) 		4 / 7 THR A  96
LEU A 100
THR A  87
VAL A  89
 None
 0.47A 1ictD-3ge2A:
undetectable		 1ictD-3ge2A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3ge2 LIPOPROTEIN,
PUTATIVE
(Streptococcus
pneumoniae) 		4 / 8 THR A  96
LEU A 100
THR A  87
VAL A  89
 None
 0.63A 4ik7B-3ge2A:
undetectable		 4ik7B-3ge2A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3ge2 LIPOPROTEIN,
PUTATIVE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 127
LEU A 151
ASP A  81
 GOL  A 203 ( 3.0A)
None
GOL  A 204 ( 4.2A)
 0.95A 5zv2A-3ge2A:
undetectable		 5zv2A-3ge2A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 3ge2 LIPOPROTEIN,
PUTATIVE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 127
VAL A 138
ASP A 140
 GOL  A 203 ( 3.0A)
None
GOL  A 203 (-3.6A)
 0.45A 6fgdA-3ge2A:
undetectable		 6fgdA-3ge2A:
16.14