SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ge6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3ge6 NITROREDUCTASE
(Exiguobacterium
sibiricum) 		4 / 7 VAL A 184
LEU A 138
SER A 136
LEU A 133
 None
 0.88A 1j8uA-3ge6A:
undetectable		 1j8uA-3ge6A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 3ge6 NITROREDUCTASE
(Exiguobacterium
sibiricum) 		3 / 3 ASP A  58
VAL A  77
PRO A  68
 None
 0.79A 2avvA-3ge6A:
undetectable		 2avvA-3ge6A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3ge6 NITROREDUCTASE
(Exiguobacterium
sibiricum) 		3 / 3 MET A  33
VAL A 151
GLU A  38
 None
 0.78A 3c6gA-3ge6A:
undetectable		 3c6gA-3ge6A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3ge6 NITROREDUCTASE
(Exiguobacterium
sibiricum) 		5 / 12 ILE A  36
LEU A 148
SER A  80
ILE A  28
ASN A  25
 None
 1.09A 4o1eA-3ge6A:
undetectable		 4o1eA-3ge6A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3ge6 NITROREDUCTASE
(Exiguobacterium
sibiricum) 		5 / 11 ILE A  84
ILE A  36
THR A  41
VAL A 184
MET A 185
 None
None
None
None
FMN  A 300 ( 4.6A)
 1.25A 5jkwA-3ge6A:
undetectable		 5jkwA-3ge6A:
18.07