SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ge9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ge9 THYMIDYLATE SYNTHASE
THYX
(Corynebacterium
glutamicum) 		4 / 8 LEU A 235
SER A 239
VAL A 206
ALA A 200
 None
 1.01A 3ax9A-3ge9A:
2.6		 3ax9A-3ge9A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ge9 THYMIDYLATE SYNTHASE
THYX
(Corynebacterium
glutamicum) 		5 / 11 GLY A  40
ASN A  57
LEU A  35
LEU A  73
LEU A  72
 None
 1.09A 3ndvA-3ge9A:
undetectable
3ndvB-3ge9A:
undetectable		 3ndvA-3ge9A:
21.22
3ndvB-3ge9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3ge9 THYMIDYLATE SYNTHASE
THYX
(Corynebacterium
glutamicum) 		5 / 11 LEU A  73
LEU A  72
GLY A  40
ASN A  57
LEU A  35
 None
 1.10A 3ndvC-3ge9A:
undetectable
3ndvD-3ge9A:
undetectable		 3ndvC-3ge9A:
21.22
3ndvD-3ge9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ge9 THYMIDYLATE SYNTHASE
THYX
(Corynebacterium
glutamicum) 		3 / 3 LEU A 175
PRO A 176
ARG A 182
 None
 0.72A 4klrB-3ge9A:
undetectable		 4klrB-3ge9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3ge9 THYMIDYLATE SYNTHASE
THYX
(Corynebacterium
glutamicum) 		3 / 3 GLU A  92
HIS A  91
ARG A  87
 None
 0.78A 5uunA-3ge9A:
undetectable		 5uunA-3ge9A:
20.13