SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 THR A 254
PRO A 256
THR A 255
 None
 0.84A 1a7yB-3gecA:
undetectable		 1a7yB-3gecA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifA-3gecA:
undetectable		 1kifA-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifB-3gecA:
undetectable		 1kifB-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifC-3gecA:
undetectable		 1kifC-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifD-3gecA:
undetectable		 1kifD-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifE-3gecA:
undetectable		 1kifE-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifF-3gecA:
undetectable		 1kifF-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifG-3gecA:
undetectable		 1kifG-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.00A 1kifH-3gecA:
undetectable		 1kifH-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 None
 0.71A 1q23C-3gecA:
undetectable		 1q23C-3gecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 None
 0.74A 1q23H-3gecA:
undetectable		 1q23H-3gecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 None
 0.74A 1q23G-3gecA:
undetectable		 1q23G-3gecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 None
 0.75A 1q23L-3gecA:
undetectable		 1q23L-3gecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 None
 0.69A 1q23J-3gecA:
undetectable		 1q23J-3gecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.02A 1ve9A-3gecA:
undetectable		 1ve9A-3gecA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 0.98A 2du8G-3gecA:
undetectable		 2du8G-3gecA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 264
ILE A 258
ARG A 272
GLY A 271
 None
 1.01A 2du8J-3gecA:
undetectable		 2du8J-3gecA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 7 TYR A 428
VAL A 435
TYR A 440
ILE A 526
 None
 1.33A 2xz5B-3gecA:
undetectable
2xz5E-3gecA:
undetectable		 2xz5B-3gecA:
20.39
2xz5E-3gecA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 7 ILE A 526
TYR A 428
VAL A 435
TYR A 440
 None
 1.36A 2xz5D-3gecA:
undetectable
2xz5E-3gecA:
undetectable		 2xz5D-3gecA:
20.39
2xz5E-3gecA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.06A 3bjwA-3gecA:
undetectable		 3bjwA-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.04A 3bjwG-3gecA:
undetectable		 3bjwG-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
ARG A 394
 None
 1.02A 3bjwC-3gecA:
undetectable		 3bjwC-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.03A 3bjwC-3gecA:
undetectable		 3bjwC-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 1.08A 3bjwD-3gecA:
undetectable		 3bjwD-3gecA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		5 / 12 ILE A 244
PHE A 274
ILE A 258
VAL A 261
LEU A 262
 None
 1.04A 3w67B-3gecA:
undetectable		 3w67B-3gecA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 7 PHE A 461
TYR A 459
TYR A 440
HIS A 395
 None
 1.17A 4g5jA-3gecA:
undetectable		 4g5jA-3gecA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 8 ARG A 422
PHE A 427
GLN A 464
GLY A 413
 None
 0.98A 4k87A-3gecA:
undetectable		 4k87A-3gecA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 7 PHE A 461
ILE A 463
TYR A 377
PHE A 391
 None
 1.09A 4o7gA-3gecA:
undetectable
4o7gB-3gecA:
undetectable		 4o7gA-3gecA:
21.71
4o7gB-3gecA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 6 PHE A 461
ILE A 463
TYR A 377
PHE A 391
 None
 1.05A 4o7gB-3gecA:
undetectable		 4o7gB-3gecA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 6 GLY A 421
PHE A 427
ILE A 424
PHE A 461
 None
 1.03A 4qogA-3gecA:
undetectable
4qogB-3gecA:
undetectable		 4qogA-3gecA:
21.71
4qogB-3gecA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 459
GLY A 491
TYR A 428
GLY A 399
 None
 1.03A 5ayfA-3gecA:
undetectable		 5ayfA-3gecA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3gec PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 LYS A 390
PRO A 389
LYS A 387
 None
 1.21A 5y9yA-3gecA:
undetectable		 5y9yA-3gecA:
21.94