SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gef'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3gef LAMIN-A/C
(Homo
sapiens) 		3 / 3 GLY A 474
ASP A 476
ASN A 524
 None
 0.64A 1vq1A-3gefA:
undetectable		 1vq1A-3gefA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 3gef LAMIN-A/C
(Homo
sapiens) 		4 / 5 LYS A 490
ASP A 461
ARG A 439
GLU A 460
 None
 1.14A 2x8oA-3gefA:
undetectable		 2x8oA-3gefA:
17.74