SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3geu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3geu INTERCELLULAR
ADHESION PROTEIN R
(Staphylococcus
aureus) 		5 / 12 TYR A  48
TYR A 153
VAL A  52
LEU A  59
GLN A 113
 None
 1.20A 1udtA-3geuA:
undetectable		 1udtA-3geuA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3geu INTERCELLULAR
ADHESION PROTEIN R
(Staphylococcus
aureus) 		4 / 7 LYS A  44
TYR A  18
GLU A 104
PRO A 103
 FMT  A 188 (-2.6A)
None
None
None
 0.98A 3hs4A-3geuA:
undetectable		 3hs4A-3geuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3geu INTERCELLULAR
ADHESION PROTEIN R
(Staphylococcus
aureus) 		4 / 7 ILE A 110
ILE A 114
LEU A  99
SER A 100
 None
 0.57A 3r9vA-3geuA:
undetectable
3r9vB-3geuA:
undetectable		 3r9vA-3geuA:
23.66
3r9vB-3geuA:
23.66