SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		4 / 8 ILE A 380
GLY A 331
LEU A 326
LEU A 363
 None
 0.81A 2vctA-3gf5A:
undetectable		 2vctA-3gf5A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		4 / 8 ILE A 380
GLY A 331
LEU A 326
LEU A 363
 None
 0.84A 2vctB-3gf5A:
undetectable		 2vctB-3gf5A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		4 / 8 ILE A 380
GLY A 331
LEU A 326
LEU A 363
 None
 0.84A 2vctC-3gf5A:
undetectable		 2vctC-3gf5A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		3 / 3 PRO A 261
LEU A 229
ARG A 230
 None
 0.92A 3aqiA-3gf5A:
undetectable		 3aqiA-3gf5A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		3 / 3 LYS A 188
ARG A 190
TRP A 196
 None
 1.18A 4i90A-3gf5A:
undetectable		 4i90A-3gf5A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		3 / 3 LYS A 132
TRP A 143
GLN A 154
 None
 1.37A 4qzuC-3gf5A:
0.0		 4qzuC-3gf5A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		3 / 3 GLU A 317
ASP A 286
PRO A 287
 None
 0.58A 6berA-3gf5A:
undetectable		 6berA-3gf5A:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 3gf5 MAJOR VAULT PROTEIN
(Mus
musculus) 		4 / 8 VAL A 159
TYR A 151
TYR A  58
GLU A 106
 None
 1.32A 6gneB-3gf5A:
undetectable		 6gneB-3gf5A:
21.03