SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 ILE A 183
THR A  76
LEU A 142
LEU A  71
ILE A 145
 None
 1.33A 1kqwA-3gf7A:
undetectable		 1kqwA-3gf7A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 LEU A 312
LEU A 414
ILE A 478
MET A 547
 None
 1.03A 1n13I-3gf7A:
undetectable
1n13L-3gf7A:
undetectable		 1n13I-3gf7A:
7.55
1n13L-3gf7A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.14A 1rl8B-3gf7A:
undetectable		 1rl8B-3gf7A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 11 PHE A 557
LEU A 414
ALA A 366
SER A 449
LEU A 450
 None
 1.13A 2bxeB-3gf7A:
undetectable		 2bxeB-3gf7A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.83A 2f8gB-3gf7A:
undetectable		 2f8gB-3gf7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.80A 2idwB-3gf7A:
undetectable		 2idwB-3gf7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.82A 2ienA-3gf7A:
undetectable		 2ienA-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 2nmzA-3gf7A:
undetectable		 2nmzA-3gf7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.83A 2nmzB-3gf7A:
undetectable		 2nmzB-3gf7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.89A 2o4lB-3gf7A:
undetectable		 2o4lB-3gf7A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 6 LEU A 144
TRP A  77
MET A  65
LEU A  71
 None
 1.46A 2oz7A-3gf7A:
undetectable		 2oz7A-3gf7A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.89A 2q63A-3gf7A:
undetectable		 2q63A-3gf7A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.81A 2q64B-3gf7A:
undetectable		 2q64B-3gf7A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.83A 2qakA-3gf7A:
undetectable		 2qakA-3gf7A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 ILE A 478
MET A 547
LEU A 312
LEU A 414
 None
 1.03A 2qqcB-3gf7A:
undetectable
2qqcC-3gf7A:
undetectable		 2qqcB-3gf7A:
12.24
2qqcC-3gf7A:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 LEU A 312
LEU A 414
ILE A 478
MET A 547
 None
 1.02A 2qqcA-3gf7A:
undetectable
2qqcF-3gf7A:
undetectable		 2qqcA-3gf7A:
7.13
2qqcF-3gf7A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 LEU A 312
LEU A 414
ILE A 478
MET A 547
 None
 1.02A 2qqcG-3gf7A:
undetectable
2qqcJ-3gf7A:
undetectable		 2qqcG-3gf7A:
7.13
2qqcJ-3gf7A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 LEU A 312
LEU A 414
ILE A 478
MET A 547
 None
 1.05A 2qqcI-3gf7A:
undetectable
2qqcL-3gf7A:
undetectable		 2qqcI-3gf7A:
7.13
2qqcL-3gf7A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.20A 2rkfB-3gf7A:
undetectable		 2rkfB-3gf7A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.21A 2rkgA-3gf7A:
undetectable		 2rkgA-3gf7A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 8 GLN A 469
GLY A 467
GLY A 419
MET A 397
 None
 0.95A 2y6rB-3gf7A:
undetectable		 2y6rB-3gf7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 ASP A 335
PHE A  10
GLY A   8
GLY A 359
MET A 574
 None
 1.46A 2y6rC-3gf7A:
undetectable		 2y6rC-3gf7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.81A 3bvbB-3gf7A:
undetectable		 3bvbB-3gf7A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.77A 3ekpD-3gf7A:
undetectable		 3ekpD-3gf7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 11 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.13A 3ektC-3gf7A:
undetectable		 3ektC-3gf7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 3ekvA-3gf7A:
undetectable		 3ekvA-3gf7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 8 ALA A 405
ASP A 407
ILE A 365
THR A 473
 None
 0.84A 3el9A-3gf7A:
undetectable		 3el9A-3gf7A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 ALA A 405
ASP A 407
GLY A 363
ILE A 365
THR A 473
 None
 1.03A 3el9B-3gf7A:
undetectable		 3el9B-3gf7A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 ILE A 110
ILE A  72
GLY A  75
TYR A 553
PRO A 552
 None
 1.31A 3elzB-3gf7A:
undetectable		 3elzB-3gf7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.87A 3em3A-3gf7A:
undetectable		 3em3A-3gf7A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 ALA A 405
ASP A 407
GLY A 363
ILE A 365
THR A 473
 None
 1.04A 3gguB-3gf7A:
undetectable		 3gguB-3gf7A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 GLU A 451
HIS A 462
THR A 453
 None
 0.88A 3hkuA-3gf7A:
undetectable		 3hkuA-3gf7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.26A 3jw2A-3gf7A:
undetectable		 3jw2A-3gf7A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.20A 3jw2B-3gf7A:
undetectable		 3jw2B-3gf7A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.83A 3k4vA-3gf7A:
undetectable		 3k4vA-3gf7A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 3k4vB-3gf7A:
undetectable		 3k4vB-3gf7A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.79A 3lzsB-3gf7A:
undetectable		 3lzsB-3gf7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.79A 3lzuA-3gf7A:
undetectable		 3lzuA-3gf7A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.16A 3lzuB-3gf7A:
undetectable		 3lzuB-3gf7A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 PHE A 268
ILE A 189
ALA A 213
THR A 192
ALA A 254
 None
 1.21A 3mdtA-3gf7A:
undetectable		 3mdtA-3gf7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.79A 3ndtA-3gf7A:
undetectable		 3ndtA-3gf7A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.82A 3ndtB-3gf7A:
undetectable		 3ndtB-3gf7A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 11 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.87A 3nu3B-3gf7A:
undetectable		 3nu3B-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.87A 3nu4B-3gf7A:
undetectable		 3nu4B-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 3nujB-3gf7A:
undetectable		 3nujB-3gf7A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.88A 3nuoB-3gf7A:
undetectable		 3nuoB-3gf7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 LEU A 181
ALA A 137
VAL A 185
ILE A 131
LEU A 178
 None
 1.05A 3ogpB-3gf7A:
undetectable		 3ogpB-3gf7A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.83A 3oxvA-3gf7A:
undetectable		 3oxvA-3gf7A:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 3oxvC-3gf7A:
undetectable		 3oxvC-3gf7A:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.88A 3s54A-3gf7A:
undetectable		 3s54A-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 3s54B-3gf7A:
undetectable		 3s54B-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.84A 3tkwB-3gf7A:
undetectable		 3tkwB-3gf7A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.81A 3tl9A-3gf7A:
undetectable		 3tl9A-3gf7A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.81A 3tl9B-3gf7A:
undetectable		 3tl9B-3gf7A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 6 ASP A 421
GLU A 427
GLY A 423
LEU A 431
 None
 1.16A 3w9tE-3gf7A:
undetectable		 3w9tE-3gf7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 371
ILE A 330
LEU A 414
ILE A 454
ILE A 316
 None
 1.13A 3zosB-3gf7A:
undetectable		 3zosB-3gf7A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 ARG A 166
ARG A 165
ILE A 131
 None
 0.75A 4b7qA-3gf7A:
undetectable		 4b7qA-3gf7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 ARG A 166
ARG A 165
ILE A 131
 None
 0.89A 4b7qC-3gf7A:
undetectable		 4b7qC-3gf7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 GLU A 451
ILE A 316
LEU A 312
GLY A 479
SER A 477
 None
 1.49A 4djfB-3gf7A:
undetectable		 4djfB-3gf7A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 10 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.80A 4dqfB-3gf7A:
undetectable		 4dqfB-3gf7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 8 LYS A 388
ILE A 385
MET A 350
GLY A 393
 None
 0.83A 4hdlA-3gf7A:
undetectable		 4hdlA-3gf7A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.80A 4hlaA-3gf7A:
undetectable		 4hlaA-3gf7A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.82A 4jecA-3gf7A:
undetectable		 4jecA-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 9 PHE A 400
CYH A 404
PHE A 339
ILE A 412
 None
 1.36A 4jvlA-3gf7A:
undetectable		 4jvlA-3gf7A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 10 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.15A 4ll3B-3gf7A:
undetectable		 4ll3B-3gf7A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 10 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.17A 4ll3A-3gf7A:
undetectable		 4ll3A-3gf7A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 8 TYR A 440
ILE A 439
VAL A 401
THR A 402
 None
 0.87A 4ma7A-3gf7A:
undetectable		 4ma7A-3gf7A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.88A 4rvjB-3gf7A:
undetectable		 4rvjB-3gf7A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 9 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.87A 4rvjD-3gf7A:
undetectable		 4rvjD-3gf7A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 5 VAL A 351
VAL A 364
GLY A 363
PHE A 339
 None
 0.97A 5d4nA-3gf7A:
undetectable
5d4nC-3gf7A:
undetectable		 5d4nA-3gf7A:
10.37
5d4nC-3gf7A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.85A 5e5jB-3gf7A:
undetectable		 5e5jB-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		6 / 12 LEU A 148
GLY A 191
ALA A 213
ASP A 212
GLY A 256
ILE A 189
 None
 1.17A 5e5kA-3gf7A:
undetectable		 5e5kA-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 11 LEU A  83
GLY A 479
ILE A  38
ASP A  37
VAL A  34
 None
 1.28A 5hjiA-3gf7A:
undetectable		 5hjiA-3gf7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 ASP A 325
ALA A 366
LYS A 396
GLU A 341
VAL A 364
 None
 1.17A 5hw4A-3gf7A:
undetectable		 5hw4A-3gf7A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 11 ASP A 325
ALA A 366
LYS A 396
GLU A 341
VAL A 364
 None
 1.16A 5hw4B-3gf7A:
undetectable		 5hw4B-3gf7A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 ASP A 325
ALA A 366
LYS A 396
GLU A 341
VAL A 364
 None
 1.18A 5hw4C-3gf7A:
undetectable		 5hw4C-3gf7A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 6 ILE A 544
GLY A  99
ASN A  98
ILE A 478
 None
 0.80A 5j4nB-3gf7A:
undetectable		 5j4nB-3gf7A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 ASP A 135
ASN A 472
PHE A 173
 None
 0.94A 5jglB-3gf7A:
undetectable		 5jglB-3gf7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 VAL A 278
ASP A 275
LEU A 207
ALA A 209
PHE A 268
 None
 1.26A 5nd4B-3gf7A:
2.4		 5nd4B-3gf7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 ASN A 398
GLN A 415
THR A 576
GLY A 353
THR A 352
 None
 1.23A 5oj0A-3gf7A:
undetectable		 5oj0A-3gf7A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.78A 5t2zB-3gf7A:
undetectable		 5t2zB-3gf7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.90A 5t8hB-3gf7A:
undetectable		 5t8hB-3gf7A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 GLY A  99
GLY A 101
VAL A 357
PHE A 334
ILE A 554
 None
 0.96A 5vimA-3gf7A:
undetectable		 5vimA-3gf7A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 GLY A  99
GLY A 101
VAL A 357
PHE A 334
ILE A 554
 None
 0.96A 5vimB-3gf7A:
undetectable		 5vimB-3gf7A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 VAL A 103
VAL A 108
ILE A 186
ILE A 282
 None
 0.80A 5ywmX-3gf7A:
undetectable		 5ywmX-3gf7A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 8 TYR A 272
GLY A 188
ILE A 189
ASP A 275
 None
 1.04A 6ag0C-3gf7A:
undetectable		 6ag0C-3gf7A:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		5 / 12 LEU A 148
GLY A 191
ALA A 213
GLY A 256
ILE A 189
 None
 0.86A 6dilB-3gf7A:
undetectable		 6dilB-3gf7A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		4 / 7 GLY A 169
THR A 170
PHE A 172
HIS A 200
 None
 0.87A 6jnhA-3gf7A:
undetectable		 6jnhA-3gf7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 ASN A 157
PRO A 124
GLN A 126
 None
 0.84A 6jnhA-3gf7A:
undetectable		 6jnhA-3gf7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A
([Clostridium]
symbiosum) 		3 / 3 ASN A 157
PRO A 124
GLN A 126
 None
 0.83A 6jogA-3gf7A:
undetectable		 6jogA-3gf7A:
14.63