SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 192
ARG A 217
ILE A 136
 None
 0.86A 1a4gB-3gf8A:
undetectable		 1a4gB-3gf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A  64
PHE A  53
VAL A  57
VAL A  39
LEU A  62
 None
 1.20A 1fe2A-3gf8A:
undetectable		 1fe2A-3gf8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 9 PHE A 292
LEU A 248
ILE A 195
VAL A 173
ILE A 290
 None
 1.35A 1gebA-3gf8A:
undetectable		 1gebA-3gf8A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A  61
LEU A  62
VAL A  39
MET A  89
 None
 1.08A 1hk1A-3gf8A:
undetectable		 1hk1A-3gf8A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 4 HIS A 204
VAL A 149
THR A 121
LEU A  72
 None
 1.34A 1oq5A-3gf8A:
undetectable		 1oq5A-3gf8A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 186
VAL A 301
ALA A 300
LEU A 299
SER A 297
 None
 1.09A 2c12C-3gf8A:
undetectable		 2c12C-3gf8A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 186
VAL A 301
ALA A 300
LEU A 299
SER A 297
 None
 1.04A 2c12F-3gf8A:
undetectable		 2c12F-3gf8A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 286
ARG A 168
LEU A 166
THR A 143
 None
 1.17A 2f78B-3gf8A:
undetectable		 2f78B-3gf8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 292
PHE A 175
HIS A 289
VAL A 305
 None
None
EDO  A   1 ( 4.7A)
None
 1.29A 3lb3B-3gf8A:
undetectable		 3lb3B-3gf8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 266
ARG A 168
ASN A 199
 None
 0.46A 3qxvD-3gf8A:
2.3		 3qxvD-3gf8A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  58
GLU A 142
GLY A 105
GLU A  78
 None
 1.41A 3w9tA-3gf8A:
undetectable		 3w9tA-3gf8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  58
GLU A 142
GLY A 105
GLU A  78
 None
 1.41A 3w9tC-3gf8A:
undetectable		 3w9tC-3gf8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  58
GLU A 142
GLY A 105
GLU A  78
 None
 1.42A 3w9tD-3gf8A:
undetectable		 3w9tD-3gf8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  58
GLU A 142
GLY A 105
GLU A  78
 None
 1.41A 3w9tG-3gf8A:
undetectable		 3w9tG-3gf8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 10 TYR A 281
TYR A 288
ILE A 290
VAL A 305
THR A 269
 None
 1.42A 5mzrA-3gf8A:
undetectable		 5mzrA-3gf8A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		5 / 10 TYR A 281
TYR A 288
ILE A 290
VAL A 305
THR A 269
 None
 1.40A 5mzrC-3gf8A:
undetectable		 5mzrC-3gf8A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  64
TYR A  98
GLN A  99
 None
 0.66A 5qgkA-3gf8A:
undetectable		 5qgkA-3gf8A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  64
TYR A  98
GLN A  99
 None
 0.65A 5qgrA-3gf8A:
undetectable		 5qgrA-3gf8A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  64
TYR A  98
GLN A  99
 None
 0.68A 5qgtA-3gf8A:
undetectable		 5qgtA-3gf8A:
23.75