SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		3 / 3 PHE A1297
LEU A1304
SER A1214
 None
 0.58A 1e7aA-3gf9A:
2.6		 1e7aA-3gf9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		4 / 7 LEU A1301
MET A1211
LEU A1217
GLU A1221
 None
 1.01A 1linA-3gf9A:
undetectable		 1linA-3gf9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 12 ILE A1336
LEU A1267
ALA A1264
THR A1192
LEU A1243
 None
 0.90A 4pssA-3gf9A:
undetectable		 4pssA-3gf9A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 ASN A1236
LEU A1239
LEU A1243
LEU A1263
LEU A1189
 None
 0.86A 4wg0B-3gf9A:
undetectable
4wg0C-3gf9A:
undetectable
4wg0D-3gf9A:
undetectable		 4wg0B-3gf9A:
3.73
4wg0C-3gf9A:
3.73
4wg0D-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 ASN A1236
LEU A1239
LEU A1243
LEU A1263
LEU A1189
 None
 0.87A 4wg0D-3gf9A:
undetectable
4wg0E-3gf9A:
undetectable
4wg0F-3gf9A:
undetectable		 4wg0D-3gf9A:
3.73
4wg0E-3gf9A:
3.73
4wg0F-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 LEU A1189
LEU A1263
ASN A1236
LEU A1239
LEU A1243
 None
 0.86A 4wg0C-3gf9A:
undetectable
4wg0D-3gf9A:
undetectable
4wg0E-3gf9A:
undetectable		 4wg0C-3gf9A:
3.73
4wg0D-3gf9A:
3.73
4wg0E-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 LEU A1189
LEU A1263
ASN A1236
LEU A1239
LEU A1243
 None
 0.88A 4wg0E-3gf9A:
undetectable
4wg0F-3gf9A:
undetectable
4wg0G-3gf9A:
undetectable		 4wg0E-3gf9A:
3.73
4wg0F-3gf9A:
3.73
4wg0G-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 LEU A1189
LEU A1263
ASN A1236
LEU A1239
LEU A1243
 None
 0.87A 4wg0G-3gf9A:
undetectable
4wg0H-3gf9A:
undetectable
4wg0I-3gf9A:
undetectable		 4wg0G-3gf9A:
3.73
4wg0H-3gf9A:
3.73
4wg0I-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 ASN A1236
LEU A1239
LEU A1243
LEU A1263
LEU A1189
 None
 0.88A 4wg0J-3gf9A:
undetectable
4wg0K-3gf9A:
undetectable
4wg0L-3gf9A:
undetectable		 4wg0J-3gf9A:
3.73
4wg0K-3gf9A:
3.73
4wg0L-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 11 LEU A1189
LEU A1263
ASN A1236
LEU A1239
LEU A1243
 None
 0.88A 4wg0I-3gf9A:
undetectable
4wg0J-3gf9A:
undetectable
4wg0K-3gf9A:
undetectable		 4wg0I-3gf9A:
3.73
4wg0J-3gf9A:
3.73
4wg0K-3gf9A:
3.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		4 / 6 TYR A1273
GLU A1193
ARG A1325
ASN A1236
 None
 1.30A 4zbqA-3gf9A:
undetectable		 4zbqA-3gf9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3gf9 INTERSECTIN 2
(Homo
sapiens) 		5 / 12 LEU A1319
GLY A1283
PHE A1226
MET A1211
LEU A1301
 UNX  A   3 (-4.5A)
UNX  A   3 (-3.4A)
None
None
None
 1.29A 5uc3B-3gf9A:
undetectable		 5uc3B-3gf9A:
17.59