SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gfh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		5 / 11 GLU A 182
ARG A  67
HIS A  75
ALA A  71
GLY A  76
 None
 1.29A 1cmaA-3gfhA:
undetectable
1cmaB-3gfhA:
undetectable		 1cmaA-3gfhA:
18.72
1cmaB-3gfhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 GLU A  83
ALA A  81
SER A  78
 None
 0.47A 1errB-3gfhA:
undetectable		 1errB-3gfhA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 ASP A  46
LEU A 151
LEU A 125
 None
 0.71A 1ikeA-3gfhA:
undetectable		 1ikeA-3gfhA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 ASP A  46
LEU A 151
LEU A 125
 None
 0.79A 1np1B-3gfhA:
undetectable		 1np1B-3gfhA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		4 / 6 PHE A 189
VAL A 152
LEU A 125
ALA A 149
 None
None
None
HG  A 800 (-2.4A)
 0.89A 2e1qA-3gfhA:
undetectable		 2e1qA-3gfhA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		4 / 6 PHE A 189
VAL A 152
LEU A 125
ALA A 149
 None
None
None
HG  A 800 (-2.4A)
 0.88A 2e1qC-3gfhA:
undetectable		 2e1qC-3gfhA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		4 / 8 PHE A 189
VAL A 152
LEU A 125
ALA A 149
 None
None
None
HG  A 800 (-2.4A)
 0.97A 3ax7A-3gfhA:
undetectable		 3ax7A-3gfhA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		4 / 7 PHE A 189
VAL A 152
LEU A 125
ALA A 149
 None
None
None
HG  A 800 (-2.4A)
 0.93A 3uniA-3gfhA:
undetectable		 3uniA-3gfhA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 VAL A 152
ALA A 188
PHE A 204
 None
 0.73A 4olbA-3gfhA:
undetectable		 4olbA-3gfhA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 VAL A 152
ALA A 188
PHE A 204
 None
 0.75A 4w5nA-3gfhA:
undetectable		 4w5nA-3gfhA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 VAL A 152
ALA A 188
PHE A 204
 None
 0.71A 4z4iA-3gfhA:
undetectable		 4z4iA-3gfhA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		4 / 8 GLY A  72
GLU A  83
TYR A  49
ASP A  46
 None
 1.06A 5gqbA-3gfhA:
undetectable		 5gqbA-3gfhA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3gfh ETHANOLAMINE
UTILIZATION PROTEIN
EUTL
(Escherichia
coli) 		3 / 3 VAL A 152
ALA A 188
PHE A 204
 None
 0.71A 5js1A-3gfhA:
undetectable		 5js1A-3gfhA:
12.96