SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gfk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J5M_A_ACTA1321_0 (CHLOROPEROXIDASE)	3gfk	REGULATORY PROTEIN SPX (Bacillus subtilis)	4 / 6	LEU A 4 PHE A 113 ILE A 110 ALA A 16	None	0.90A	2j5mA-3gfkA: undetectable	2j5mA-3gfkA: 17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA504_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	3gfk	REGULATORY PROTEIN SPX (Bacillus subtilis)	4 / 8	LEU A 82 ILE A 83 ILE A 57 THR A 53	None	0.79A	4em2A-3gfkA: undetectable	4em2A-3gfkA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODI_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3gfk	REGULATORY PROTEIN SPX (Bacillus subtilis)	3 / 3	HIS A 23 GLU A 22 TRP A 19	None	0.74A	5odiD-3gfkA: undetectable	5odiD-3gfkA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODQ_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3gfk	REGULATORY PROTEIN SPX (Bacillus subtilis)	3 / 3	HIS A 23 GLU A 22 TRP A 19	None	0.72A	5odqD-3gfkA: undetectable	5odqD-3gfkA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODR_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3gfk	REGULATORY PROTEIN SPX (Bacillus subtilis)	3 / 3	HIS A 23 GLU A 22 TRP A 19	None	0.68A	5odrD-3gfkA: undetectable	5odrD-3gfkA: 18.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2J5M_A_ACTA1321_0","CHLOROPEROXIDASE","3gfk","REGULATORY PROTEIN SPX","Bacillus subtilis",4,"LEU A   4;PHE A 113;ILE A 110;ALA A  16","None","0.90A","2j5mA-3gfkA:undetectable","2j5mA-3gfkA:17.79"],["4EM2_A_SALA504_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","3gfk","REGULATORY PROTEIN SPX","Bacillus subtilis",4,"LEU A  82;ILE A  83;ILE A  57;THR A  53","None","0.79A","4em2A-3gfkA:undetectable","4em2A-3gfkA:22.47"],["5ODI_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3gfk","REGULATORY PROTEIN SPX","Bacillus subtilis",3,"HIS A  23;GLU A  22;TRP A  19","None","0.74A","5odiD-3gfkA:undetectable","5odiD-3gfkA:18.92"],["5ODQ_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3gfk","REGULATORY PROTEIN SPX","Bacillus subtilis",3,"HIS A  23;GLU A  22;TRP A  19","None","0.72A","5odqD-3gfkA:undetectable","5odqD-3gfkA:18.92"],["5ODR_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3gfk","REGULATORY PROTEIN SPX","Bacillus subtilis",3,"HIS A  23;GLU A  22;TRP A  19","None","0.68A","5odrD-3gfkA:undetectable","5odrD-3gfkA:18.92"]]