SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gfo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 12 ILE A 197
ILE A 180
ILE A 152
LEU A 156
ILE A 193
 None
 0.86A 1oipA-3gfoA:
2.7		 1oipA-3gfoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		4 / 8 VAL A 157
VAL A 104
LEU A 156
ASP A 103
 None
 0.92A 2ddwA-3gfoA:
undetectable		 2ddwA-3gfoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		4 / 8 PHE A  49
THR A  35
VAL A 162
ILE A 164
 None
 0.97A 2qbmA-3gfoA:
undetectable		 2qbmA-3gfoA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 12 LEU A 207
LEU A  48
ILE A 196
ILE A  25
VAL A 229
 None
 1.12A 2ygnA-3gfoA:
undetectable		 2ygnA-3gfoA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 GLY A 154
ASP A 103
ILE A 131
LEU A 126
THR A 129
 None
 1.38A 3bexC-3gfoA:
undetectable
3bexD-3gfoA:
undetectable		 3bexC-3gfoA:
23.78
3bexD-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 10 LEU A 126
THR A 129
GLY A 154
ASP A 103
ILE A 131
 None
 1.38A 3bexC-3gfoA:
undetectable
3bexD-3gfoA:
undetectable		 3bexC-3gfoA:
23.78
3bexD-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 10 GLY A 154
ASP A 103
ILE A 131
LEU A 126
THR A 129
 None
 1.38A 3bexE-3gfoA:
undetectable
3bexF-3gfoA:
undetectable		 3bexE-3gfoA:
23.78
3bexF-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 LEU A 126
THR A 129
GLY A 154
ASP A 103
ILE A 131
 None
 1.38A 3bexE-3gfoA:
undetectable
3bexF-3gfoA:
undetectable		 3bexE-3gfoA:
23.78
3bexF-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 GLY A 154
ASP A 103
ILE A 131
LEU A 126
THR A 129
 None
 1.39A 3bf1A-3gfoA:
undetectable
3bf1B-3gfoA:
undetectable		 3bf1A-3gfoA:
23.78
3bf1B-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 GLY A 154
ASP A 103
ILE A 131
LEU A 126
THR A 129
 None
 1.37A 3bf1C-3gfoA:
undetectable
3bf1D-3gfoA:
undetectable		 3bf1C-3gfoA:
23.78
3bf1D-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 LEU A 126
THR A 129
GLY A 154
ASP A 103
ILE A 131
 None
 1.40A 3bf1C-3gfoA:
undetectable
3bf1D-3gfoA:
undetectable		 3bf1C-3gfoA:
23.78
3bf1D-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 GLY A 154
ASP A 103
ILE A 131
LEU A 126
THR A 129
 None
 1.38A 3bf1E-3gfoA:
undetectable
3bf1F-3gfoA:
undetectable		 3bf1E-3gfoA:
23.78
3bf1F-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 11 LEU A 126
THR A 129
GLY A 154
ASP A 103
ILE A 131
 None
 1.36A 3bf1E-3gfoA:
undetectable
3bf1F-3gfoA:
undetectable		 3bf1E-3gfoA:
23.78
3bf1F-3gfoA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		5 / 10 VAL A   8
ALA A  36
ILE A  37
LEU A  48
PHE A  52
 None
 1.23A 3fl9F-3gfoA:
undetectable		 3fl9F-3gfoA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		4 / 5 LYS A 137
PRO A 138
SER A  97
LEU A 134
 None
 1.22A 3iluH-3gfoA:
undetectable		 3iluH-3gfoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		4 / 5 VAL A 150
THR A 139
ASP A  92
LEU A  95
 None
 1.29A 5m0iB-3gfoA:
undetectable		 5m0iB-3gfoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1
(Clostridium
perfringens) 		3 / 3 LEU A  48
SER A  46
PHE A  49
 None
SO4  A 274 (-2.7A)
None
 0.66A 6fgcA-3gfoA:
undetectable		 6fgcA-3gfoA:
23.72