SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 LEU A  65
PRO A  66
LEU A  69
 None
 0.54A 1hrkA-3gfvA:
2.7		 1hrkA-3gfvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 5 SER A 245
TYR A 275
SER A 217
ASP A 181
 None
PO4  A 304 (-4.5A)
None
None
 1.36A 1vidA-3gfvA:
undetectable		 1vidA-3gfvA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 6 SER A 245
TYR A 275
SER A 217
ASP A 181
 None
PO4  A 304 (-4.5A)
None
None
 1.33A 2cl5B-3gfvA:
undetectable		 2cl5B-3gfvA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		5 / 11 ILE A 142
GLY A  27
THR A  28
HIS A  21
LEU A 121
 None
 1.42A 2fn1A-3gfvA:
undetectable		 2fn1A-3gfvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 6 SER A 245
TYR A 275
SER A 217
ASP A 181
 None
PO4  A 304 (-4.5A)
None
None
 1.34A 2zvjA-3gfvA:
undetectable		 2zvjA-3gfvA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 8 THR A 226
LEU A 175
LEU A 231
ILE A 177
 None
 0.93A 3nbqC-3gfvA:
undetectable		 3nbqC-3gfvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 TYR A  68
ASP A  41
ASP A  46
 None
 0.85A 3r24A-3gfvA:
undetectable		 3r24A-3gfvA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 SER A  70
ASP A 270
ASP A 235
 None
 0.89A 3uj7A-3gfvA:
undetectable		 3uj7A-3gfvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 5 ASP A  41
SER A 277
GLY A 278
ASP A 135
 None
 1.28A 3w9tB-3gfvA:
undetectable		 3w9tB-3gfvA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 5 ASP A  41
SER A 277
GLY A 278
ASP A 135
 None
 1.28A 3w9tC-3gfvA:
undetectable		 3w9tC-3gfvA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 5 ASP A  41
SER A 277
GLY A 278
ASP A 135
 None
 1.28A 3w9tD-3gfvA:
undetectable		 3w9tD-3gfvA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		5 / 9 GLY A  43
SER A  44
TYR A 128
ASP A 135
GLY A 280
 None
 1.15A 4lb0A-3gfvA:
undetectable		 4lb0A-3gfvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		5 / 12 VAL A  80
ILE A 115
PHE A 143
ALA A  58
LEU A  94
 None
 1.09A 4o1zB-3gfvA:
undetectable		 4o1zB-3gfvA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 SER A 283
TYR A  68
ASP A  41
 None
 0.84A 4rp8C-3gfvA:
0.8		 4rp8C-3gfvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 5 SER A 245
TYR A 275
SER A 217
ASP A 181
 None
PO4  A 304 (-4.5A)
None
None
 1.34A 5fhrA-3gfvA:
undetectable		 5fhrA-3gfvA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		4 / 8 TYR A  68
ASP A  46
THR A  47
VAL A  39
 None
 1.17A 5ov9B-3gfvA:
undetectable		 5ov9B-3gfvA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 MET A 287
ASP A  46
ARG A 104
 None
None
PO4  A 304 (-4.0A)
 1.12A 5z6jA-3gfvA:
undetectable		 5z6jA-3gfvA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ
(Bacillus
subtilis) 		3 / 3 ARG A 236
HIS A 214
ARG A 192
 None
PO4  A 304 (-3.9A)
PO4  A 304 (-3.0A)
 0.70A 6dwdD-3gfvA:
undetectable		 6dwdD-3gfvA:
19.60