SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 9 LEU A 423
ILE A 420
LEU A 465
VAL A 468
GLY A 401
 None
 1.26A 1e7aA-3gg2A:
undetectable		 1e7aA-3gg2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 9 LEU A 423
ILE A 420
LEU A 465
VAL A 468
GLY A 401
 None
 1.26A 1e7aB-3gg2A:
undetectable		 1e7aB-3gg2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		3 / 3 TRP A 400
ALA A 464
VAL A 459
 None
 0.87A 1kqeA-3gg2A:
undetectable
1kqeE-3gg2A:
undetectable		 1kqeA-3gg2A:
2.30
1kqeE-3gg2A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 11 ALA A  98
LEU A 129
ILE A 133
ILE A  86
PHE A 144
 None
 1.08A 2w9sA-3gg2A:
undetectable		 2w9sA-3gg2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 PRO A 415
PHE A 466
GLY A 494
THR A 469
LEU A 509
 None
 1.22A 2zifA-3gg2A:
undetectable		 2zifA-3gg2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 10 ILE A 160
THR A 196
ILE A 158
ILE A 184
SER A 183
 None
 1.46A 3kpbD-3gg2A:
undetectable		 3kpbD-3gg2A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 9 LEU A 380
PRO A 415
LEU A 419
HIS A 467
LEU A 402
 None
 1.44A 3q1eB-3gg2A:
undetectable
3q1eD-3gg2A:
undetectable		 3q1eB-3gg2A:
14.83
3q1eD-3gg2A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		4 / 8 TYR A 456
TRP A 479
LEU A 465
MET A 486
 None
 1.16A 3uzzB-3gg2A:
undetectable		 3uzzB-3gg2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
ASP A 493
HIS A 467
PHE A 474
GLY A 494
 None
 1.30A 4bz6C-3gg2A:
undetectable		 4bz6C-3gg2A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
ASP A 493
HIS A 467
PHE A 474
GLY A 494
 None
 1.22A 4lxzC-3gg2A:
undetectable		 4lxzC-3gg2A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		3 / 3 LEU A  91
MET A 132
TYR A 125
 None
 0.70A 4p6xG-3gg2A:
undetectable		 4p6xG-3gg2A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
ASP A 493
HIS A 467
PHE A 474
GLY A 494
 None
 1.29A 4qa0A-3gg2A:
2.6		 4qa0A-3gg2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
HIS A 467
PHE A 474
ASP A 493
GLY A 494
 None
 1.35A 4qa0A-3gg2A:
2.6		 4qa0A-3gg2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
ASP A 493
HIS A 467
PHE A 474
GLY A 494
 None
 1.24A 4qa2A-3gg2A:
2.5		 4qa2A-3gg2A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 401
ASP A 493
HIS A 467
PHE A 474
GLY A 494
 None
 1.25A 4qa2B-3gg2A:
undetectable		 4qa2B-3gg2A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		4 / 7 ALA A  82
ARG A 186
GLY A 185
GLU A 215
 None
 0.86A 5bs8A-3gg2A:
undetectable
5bs8C-3gg2A:
undetectable
5bs8D-3gg2A:
undetectable		 5bs8A-3gg2A:
24.00
5bs8C-3gg2A:
24.00
5bs8D-3gg2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		4 / 6 ALA A  82
ARG A 186
GLY A 185
GLU A 215
 None
 0.83A 5btgA-3gg2A:
undetectable
5btgB-3gg2A:
undetectable
5btgC-3gg2A:
undetectable		 5btgA-3gg2A:
24.00
5btgB-3gg2A:
21.71
5btgC-3gg2A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY
(Porphyromonas
gingivalis) 		5 / 12 ARG A 395
VAL A 397
GLU A 463
ALA A 464
LEU A 419
 None
 1.14A 6f6iA-3gg2A:
undetectable
6f6iB-3gg2A:
undetectable		 6f6iA-3gg2A:
11.90
6f6iB-3gg2A:
9.98