SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 THR A 375
GLU A 459
HIS A 460
LEU A 425
None
0.88A 1d4fC-3gg4A:
undetectable
1d4fC-3gg4A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 8 GLY A 448
GLU A 475
SER A 474
TYR A 354
None
0.95A 1maaD-3gg4A:
undetectable
1maaD-3gg4A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 VAL A 106
SER A  48
ASP A 167
GLN A 141
None
1.30A 1n2xB-3gg4A:
undetectable
1n2xB-3gg4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 MET A 535
ARG A 391
ILE A 136
HIS A 112
None
1.46A 1osvB-3gg4A:
0.0
1osvB-3gg4A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 LEU A 425
PHE A 527
ARG A 388
None
0.86A 1xdkB-3gg4A:
undetectable
1xdkB-3gg4A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 GLN A 538
HIS A 534
ARG A 391
None
0.74A 1zlqA-3gg4A:
undetectable
1zlqA-3gg4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A 133
GLY A 320
GLY A 302
GLU A 319
ILE A 441
None
0.89A 2oxtA-3gg4A:
undetectable
2oxtA-3gg4A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 11 ASN A 395
LEU A 146
THR A 189
VAL A 128
LEU A 129
None
1.22A 3a51A-3gg4A:
undetectable
3a51A-3gg4A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 ASN A 395
LEU A 146
THR A 189
VAL A 128
LEU A 129
None
1.14A 3a51D-3gg4A:
undetectable
3a51D-3gg4A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 11 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.05A 3g88A-3gg4A:
undetectable
3g88A-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 11 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.03A 3g88B-3gg4A:
undetectable
3g88B-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.04A 3g89A-3gg4A:
undetectable
3g89A-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 11 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.05A 3g89B-3gg4A:
undetectable
3g89B-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.08A 3g8bA-3gg4A:
undetectable
3g8bA-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A  77
ALA A 173
THR A 170
ALA A 238
ALA A 489
None
1.05A 3g8bB-3gg4A:
undetectable
3g8bB-3gg4A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 10 GLN A 150
LEU A 162
VAL A 159
VAL A  86
LEU A  84
None
0.97A 3gwxA-3gg4A:
undetectable
3gwxA-3gg4A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 LYS A 223
PRO A 224
LEU A 229
SER A 250
None
1.43A 3ijxH-3gg4A:
undetectable
3ijxH-3gg4A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 LYS A 223
PRO A 224
LEU A 229
SER A 250
None
1.44A 3iluH-3gg4A:
undetectable
3iluH-3gg4A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 11 LEU A 233
ALA A  58
LEU A 165
PHE A  78
THR A 174
None
1.33A 3jwqB-3gg4A:
undetectable
3jwqC-3gg4A:
undetectable
3jwqB-3gg4A:
20.80
3jwqC-3gg4A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 VAL A  85
SER A  48
LEU A  87
None
0.76A 3n8xA-3gg4A:
undetectable
3n8xA-3gg4A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 ILE A 353
MET A 412
ILE A 378
ILE A 333
TYR A 339
None
1.22A 3ohtA-3gg4A:
undetectable
3ohtB-3gg4A:
undetectable
3ohtA-3gg4A:
23.01
3ohtB-3gg4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 10 ILE A 378
ILE A 333
TYR A 339
ILE A 353
MET A 412
None
1.22A 3ohtA-3gg4A:
undetectable
3ohtB-3gg4A:
undetectable
3ohtA-3gg4A:
23.01
3ohtB-3gg4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLN A 322
PHE A 456
THR A 451
GLY A 284
ALA A 446
None
1.00A 3tegA-3gg4A:
undetectable
3tegA-3gg4A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 6 GLN A 322
PHE A 527
PRO A 382
LEU A 425
None
1.39A 3tgvB-3gg4A:
undetectable
3tgvB-3gg4A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 ASN A 122
ALA A 118
ARG A 388
ALA A 392
None
0.93A 3twpA-3gg4A:
undetectable
3twpA-3gg4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 SER A 389
GLY A 426
THR A 427
ILE A 430
None
0.65A 4acaC-3gg4A:
undetectable
4acaC-3gg4A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 PHE A 527
ASP A 521
ARG A 428
None
0.87A 4eahF-3gg4A:
6.5
4eahF-3gg4A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 PHE A 527
ASP A 521
ARG A 428
None
0.86A 4eahG-3gg4A:
6.3
4eahG-3gg4A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 GLY A 284
ALA A 476
SER A 447
GLU A 475
None
0.88A 4hyfA-3gg4A:
undetectable
4hyfA-3gg4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 8 GLY A 284
ALA A 476
SER A 447
GLU A 475
None
0.87A 4hyfB-3gg4A:
undetectable
4hyfB-3gg4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 8 GLY A 284
ALA A 476
SER A 447
GLU A 475
None
0.85A 4hyfC-3gg4A:
undetectable
4hyfC-3gg4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 5 LEU A 317
ARG A 388
PRO A 166
SER A 252
None
1.30A 4kmmB-3gg4A:
undetectable
4kmmB-3gg4A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
3 / 3 ASP A 255
TRP A 304
SER A 287
None
1.10A 4lrhF-3gg4A:
undetectable
4lrhF-3gg4A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 GLY A 449
GLY A 285
SER A 287
GLU A 475
None
0.69A 5izfA-3gg4A:
undetectable
5izfA-3gg4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A 485
ALA A 482
PHE A  78
HIS A 257
CYH A 182
None
1.42A 5wbvA-3gg4A:
undetectable
5wbvA-3gg4A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 GLY A 485
ALA A 482
PHE A  78
HIS A 257
CYH A 182
None
1.40A 5wbvB-3gg4A:
undetectable
5wbvB-3gg4A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 LEU A 264
ILE A 261
THR A 260
TYR A 315
None
1.03A 5zsfA-3gg4A:
undetectable
5zsfB-3gg4A:
undetectable
5zsfA-3gg4A:
9.64
5zsfB-3gg4A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
4 / 7 ARG A  25
GLU A 473
ARG A 504
PRO A 471
None
1.09A 6a4iB-3gg4A:
undetectable
6a4iB-3gg4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 HIS A 460
GLY A 285
GLY A 326
ALA A 327
ASP A 255
None
1.13A 6b3aA-3gg4A:
undetectable
6b3aA-3gg4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 HIS A 460
GLY A 285
GLY A 326
ALA A 327
ASP A 255
None
1.18A 6b3bA-3gg4A:
undetectable
6b3bA-3gg4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 12 HIS A 460
GLY A 285
GLY A 326
ALA A 327
ILE A 283
None
1.19A 6b3bA-3gg4A:
undetectable
6b3bA-3gg4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 9 ALA A 476
ALA A 258
GLY A 262
ALA A 482
SER A 481
None
1.21A 6bklE-3gg4A:
undetectable
6bklF-3gg4A:
undetectable
6bklG-3gg4A:
undetectable
6bklH-3gg4A:
undetectable
6bklE-3gg4A:
4.84
6bklF-3gg4A:
4.84
6bklG-3gg4A:
4.84
6bklH-3gg4A:
4.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)
3gg4 GLYCEROL KINASE
(Yersinia
pseudotuberculos
is)
5 / 10 GLY A  77
GLY A   7
ALA A 482
THR A 486
GLY A  75
None
1.14A 6e5zA-3gg4A:
undetectable
6e5zA-3gg4A:
16.45