SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE4_B_T44B328_1 (TRANSTHYRETIN)	3gg6	NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18 (Homo sapiens)	4 / 8	GLU A 91 LEU A 98 GLU A 62 ALA A 142	None	0.92A	1ie4B-3gg6A: undetectable 1ie4D-3gg6A: undetectable	1ie4B-3gg6A: 25.00 1ie4D-3gg6A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3gg6	NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18 (Homo sapiens)	5 / 12	LEU A 88 VAL A 92 VAL A 119 PHE A 50 ALA A 142	None	1.27A	4nc3A-3gg6A: undetectable	4nc3A-3gg6A: 17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_R_BEZR801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	3gg6	NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18 (Homo sapiens)	4 / 7	PHE A 120 ALA A 48 PRO A 102 LEU A 121	None	1.12A	5dzkD-3gg6A: undetectable 5dzkR-3gg6A: undetectable	5dzkD-3gg6A: 19.16 5dzkR-3gg6A: 5.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IE4_B_T44B328_1","TRANSTHYRETIN;TRANSTHYRETIN","3gg6","NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18","Homo sapiens",4,"GLU A  91;LEU A  98;GLU A  62;ALA A 142","None","0.92A","1ie4B-3gg6A:undetectable;1ie4D-3gg6A:undetectable","1ie4B-3gg6A:25.00;1ie4D-3gg6A:25.00"],["4NC3_A_ERMA1202_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3gg6","NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18","Homo sapiens",5,"LEU A  88;VAL A  92;VAL A 119;PHE A  50;ALA A 142","None","1.27A","4nc3A-3gg6A:undetectable","4nc3A-3gg6A:17.40"],["5DZK_R_BEZR801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","3gg6","NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 18","Homo sapiens",4,"PHE A 120;ALA A  48;PRO A 102;LEU A 121","None","1.12A","5dzkD-3gg6A:undetectable;5dzkR-3gg6A:undetectable","5dzkD-3gg6A:19.16;5dzkR-3gg6A:5.56"]]