SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 5 HIS A   5
HIS A  58
HIS A 122
ASP A 194
 MN  A 253 (-3.3A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-2.7A)
 0.73A 1e9yB-3gg7A:
12.3		 1e9yB-3gg7A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 6 HIS A   5
HIS A   7
HIS A  58
HIS A 122
ASP A 194
 MN  A 253 (-3.3A)
MN  A 253 (-3.3A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-2.7A)
 0.74A 1fweC-3gg7A:
11.9		 1fweC-3gg7A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLU A  84
HIS A  58
HIS A 122
HIS A 146
ASP A 194
 MN  A 253 (-2.6A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-4.3A)
MN  A 253 (-2.7A)
 1.11A 1ituA-3gg7A:
12.5		 1ituA-3gg7A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLU A  84
HIS A  58
HIS A 122
HIS A 146
ASP A 194
 MN  A 253 (-2.6A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-4.3A)
MN  A 253 (-2.7A)
 1.13A 1ituB-3gg7A:
12.3		 1ituB-3gg7A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 ASP A   3
ILE A 118
LEU A 239
ILE A 144
THR A 193
 None
 1.01A 1ra2A-3gg7A:
undetectable		 1ra2A-3gg7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 ASP A   3
ILE A 118
LEU A 239
ILE A 144
THR A 193
 None
 1.01A 1rb2A-3gg7A:
undetectable		 1rb2A-3gg7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.19A 2obvA-3gg7A:
undetectable		 2obvA-3gg7A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.23A 2p02A-3gg7A:
undetectable		 2p02A-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		3 / 3 PRO A 143
PHE A 165
ALA A 158
 None
 0.64A 3itaD-3gg7A:
undetectable		 3itaD-3gg7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 HIS A 146
ASP A 194
HIS A   7
ASP A  88
LEU A  93
 MN  A 253 (-4.3A)
MN  A 253 (-2.7A)
MN  A 253 (-3.3A)
None
None
 1.44A 3lmyA-3gg7A:
2.5		 3lmyA-3gg7A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 11 LEU A 217
MET A 171
VAL A 172
GLY A 177
ALA A 178
 None
 1.22A 3pghB-3gg7A:
undetectable		 3pghB-3gg7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		3 / 3 ARG A  65
PRO A  70
PHE A  57
 None
 0.92A 3thrC-3gg7A:
undetectable		 3thrC-3gg7A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 5 HIS A   5
HIS A  58
HIS A 122
ASP A 194
 MN  A 253 (-3.3A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-2.7A)
 0.66A 4h9mA-3gg7A:
5.7		 4h9mA-3gg7A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.18A 4kttA-3gg7A:
undetectable		 4kttA-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.19A 4kttC-3gg7A:
undetectable		 4kttC-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 10 ASP A   3
PRO A  14
VAL A  17
ALA A  18
GLY A 195
 None
 1.01A 4mmdA-3gg7A:
undetectable		 4mmdA-3gg7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 ASP A   3
PRO A  14
VAL A  17
ALA A  18
GLY A 195
 None
 0.99A 4mmdB-3gg7A:
undetectable		 4mmdB-3gg7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.18A 4ndnA-3gg7A:
undetectable		 4ndnA-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 6 HIS A   5
HIS A   7
HIS A  58
HIS A 122
ASP A 194
 MN  A 253 (-3.3A)
MN  A 253 (-3.3A)
MRD  A 257 (-3.5A)
None
MN  A 253 (-2.7A)
 0.67A 4ubpC-3gg7A:
9.8		 4ubpC-3gg7A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.21A 5a1iA-3gg7A:
undetectable		 5a1iA-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 6 HIS A 122
HIS A   7
HIS A   5
HIS A  58
 None
MN  A 253 (-3.3A)
MN  A 253 (-3.3A)
MRD  A 257 (-3.5A)
 1.07A 5nelB-3gg7A:
4.3
5nelC-3gg7A:
2.3		 5nelB-3gg7A:
21.55
5nelC-3gg7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 5 THR A  33
HIS A   5
ASP A 194
HIS A 146
 MRD  A 257 ( 4.5A)
MN  A 253 (-3.3A)
MN  A 253 (-2.7A)
MN  A 253 (-4.3A)
 0.85A 6dchA-3gg7A:
undetectable		 6dchA-3gg7A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.21A 6fboA-3gg7A:
undetectable		 6fboA-3gg7A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		5 / 12 ASP A 194
HIS A  58
PRO A  59
SER A 120
SER A 166
 MN  A 253 (-2.7A)
MRD  A 257 (-3.5A)
None
None
None
 1.47A 6fbpA-3gg7A:
undetectable
6fbpB-3gg7A:
undetectable		 6fbpA-3gg7A:
14.52
6fbpB-3gg7A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.10A 6fcbA-3gg7A:
undetectable		 6fcbA-3gg7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gg7 UNCHARACTERIZED
METALLOPROTEIN
(Deinococcus
radiodurans) 		4 / 8 PRO A 207
ASP A   3
SER A 166
SER A 120
 None
 1.18A 6fcdA-3gg7A:
undetectable		 6fcdA-3gg7A:
14.52